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Machine translation
1. (WO1992011264) PROCESS FOR THE PREPARATION OF THE MACROLIDE VS 48926 AND RELATED COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1992/011264    International Application No.:    PCT/GB1991/002284
Publication Date: 09.07.1992 International Filing Date: 19.12.1991
Chapter 2 Demand Filed:    01.06.1992    
IPC:
C07D 493/14 (2006.01)
Applicants: BEECHAM GROUP PLC [GB/GB]; Four New Horizons Court, Harlequin Avenue, Brentford, Middlesex TW8 9EP (GB) (For All Designated States Except US).
DORGAN, Roderick, John [GB/GB]; (GB) (For US Only).
MORGAN, David, Owen [GB/GB]; (GB) (For US Only).
HUSSAIN, Nigel [GB/GB]; (GB) (For US Only)
Inventors: DORGAN, Roderick, John; (GB).
MORGAN, David, Owen; (GB).
HUSSAIN, Nigel; (GB)
Agent: WEST, Vivien; SmithKline Beecham, Corporate Patents, Great Burgh, Yew Tree Bottom Road, Epsom, Surrey KT18 5XQ (GB)
Priority Data:
9027725.2 20.12.1990 GB
Title (EN) PROCESS FOR THE PREPARATION OF THE MACROLIDE VS 48926 AND RELATED COMPOUNDS
(FR) PROCEDE DE PREPARATION DU MACROLIDE VS 48926 ET DE COMPOSES ASSOCIES
Abstract: front page image
(EN)A process for the preparation of a compound of formula (I), wherein R?1¿ is optionally protected hydroxy or methoxy and R?2¿ is hydrogen or 4'-($g(a)-$i(L)-oleandrosyl)-$g(a)$i(L)-oleandrosyloxy, comprises the oxidation of a compound of formula (II), wherein R?4¿ is hydrogen, or C¿1-6? alkyl, such as methyl, optionally substituted by one or more of hydroxy, alkoxy, alkylthio, oxo, halogen and trifluoromethyl.
(FR)Procédé de préparation d'un composé de formule (I), dans laquelle R?1¿ est hydroxy ou méthoxy protégé et R?2¿ est hydrogène ou 4'-($g(a)-$i(L)-oléandroxyl)-$g(a)$i(L)-oléandrosyloxy; et qui comprend l'oxydation d'un composé de formule (II), dans laquelle R?4¿ est hydrogène, ou alkyle C¿1-6?, tel que méthyle, à substitution optionnelle par un ou plusieurs des éléments parmi hydroxy, alkoxy, alkylthio, oxo, halogène et trifluorométhyle.
Designated States: AU, CA, JP, KR, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, MC, NL, SE).
Publication Language: English (EN)
Filing Language: English (EN)