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1. (WO1992010760) METHODS FOR THE DIAGNOSIS OF CHRONIC LOWER BACK AND CERVICAL PAIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/010760 International Application No.: PCT/US1991/008552
Publication Date: 25.06.1992 International Filing Date: 15.11.1991
Chapter 2 Demand Filed: 26.06.1992
IPC:
C07K 16/18 (2006.01) ,G01N 33/561 (2006.01) ,G01N 33/68 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
558
using diffusion or migration of antigen or antibody
561
Immunoelectrophoresis
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
MONOCLONETICS INTERNATIONAL, INCORPORATED [US/US]; 515 Post Oak Blvd. Suite 104 Houston, TX 77027, US (AllExceptUS)
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; Washington, DC, US (AllExceptUS)
CAMERON, Bruce, M., Sr. [US/US]; US (UsOnly)
MERRIL, Carl, R. [US/US]; US (UsOnly)
CREED, Guy, Joseph [US/US]; US (UsOnly)
VANDERPUTTEN, Dale [US/US]; US (UsOnly)
Inventors:
CAMERON, Bruce, M., Sr.; US
MERRIL, Carl, R.; US
CREED, Guy, Joseph; US
VANDERPUTTEN, Dale; US
Agent:
GORMLEY, Mary, E.; Nikaido, Marmelstein, Murray & Oram Metropolitan Square 655 Fifteenth Street, N.W. Suite 330 - G Street Lobby Washington, DC 20005-5701, US
Priority Data:
620,10430.11.1990US
Title (EN) METHODS FOR THE DIAGNOSIS OF CHRONIC LOWER BACK AND CERVICAL PAIN
(FR) PROCEDES DE DIAGNOSTIC POUR LES DOULEURS CERVICALES ET DU BAS DU DOS DE TYPE CHRONIQUE
Abstract:
(EN) Methods of diagnosing and monitoring chronic back and cervical pain are disclosed. The methods involved subjecting a body fluid sample from a patient suspected of having chronic lower back or cervical pain to two-dimensional electrophoresis or an immunoassay and measuring relative amounts of protein or proteins which increase or decrease in concentration as compared to a standard control. Also disclosed are kits for use with the diagnostic methods.
(FR) L'invention se rapporte à des procédés de diagnostic et de contrôle pour les douleurs lombaires et cervicales de type chronique, qui consistent à soumettre un échantillon de fluide corporel d'un patient supposé souffrir de douleurs cervicales ou du bas du dos du type chronique à une électrophorèse bidimensionnelle ou à une immunoanalyse, puis à mesurer les quantités relatives de protéine(s) dont la concentration augmente ou diminue par rapport à un témoin standard. L'invention décrit également des kits à utiliser avec ces procédés de diagnostic.
Designated States: AU, CA, JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0559795US5364793US5583201US5844097JPH06503418CA2097426
AU1991091169