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1. (WO1992010759) DIAGNOSTIC TEST
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/010759 International Application No.: PCT/GB1991/002228
Publication Date: 25.06.1992 International Filing Date: 13.12.1991
Chapter 2 Demand Filed: 02.07.1992
IPC:
C12Q 1/26 (2006.01) ,C12Q 1/28 (2006.01) ,G01N 33/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
26
involving oxidoreductase
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
26
involving oxidoreductase
28
involving peroxidase
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
BRITISH TECHNOLOGY GROUP LTD. [GB/GB]; 101 Newington Causeway London SE1 6BU, GB (AllExceptUS)
DAVIES, Michael, Jonathan [GB/GB]; GB (UsOnly)
RICE-EVANS, Catherine, Anne [GB/GB]; GB (UsOnly)
Inventors:
DAVIES, Michael, Jonathan; GB
RICE-EVANS, Catherine, Anne; GB
Agent:
EYLES, Winifred; Patents Department British Technology Group Ltd. 101 Newington Causeway London SE1 6BU, GB
Priority Data:
9027131.314.12.1990GB
Title (EN) DIAGNOSTIC TEST
(FR) TEST DIAGNOSTIQUE
Abstract:
(EN) A diagnostic test can determine the occurrence of myocardial infarction or the total plasma antioxidant status as a marker of predisposition to such an event, or the antioxidant status of other clinical an non-clinical samples. The test involves contacting a clinical sample in the presence of myoglobin and an oxidant therefor with a compoud which reacts in that environment to form a chromogenic species with a characteristic absorption band in the visible spectrum spaced from potentially interfering bands attributable to haem proteins and other blood components.
(FR) L'invention se rapporte à un test diagnostique pour déterminer si un infarctus du myocarde s'est produit ou pour déterminer l'état anti-oxydant total du plasma, comme signe de prédisposition à une telle éventualité, ou l'état anti-oxydant d'autres échantillons cliniques et non cliniques. Ce test consiste à mettre en contact un échantillon clinique, en présence de myoglobine et d'un oxydant de celle-ci, avec un composé qui réagit dans ce milieu, pour former une espèce chromogène possédant une bande d'absorption caractéristique dans le spectre visible éloignée des bandes d'interférence potentielle attribuables aux protéines hématiques et à d'autres constituants du sang.
Designated States: JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, MC, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0563114US5427951