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1. (WO1992010571) HUMAN DOPAMINE D¿4? RECEPTOR AND ITS USES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/010571 International Application No.: PCT/US1991/009308
Publication Date: 25.06.1992 International Filing Date: 06.12.1991
Chapter 2 Demand Filed: 25.06.1992
IPC:
C07K 14/705 (2006.01) ,C12Q 1/68 (2006.01) ,G01N 33/94 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
94
involving narcotics
Applicants:
STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION on behalf of THE OREGON HEALTH SCIENCES UNIVERSITY [US/US]; 1431 Johnson Lane Eugene, OR 97403, US
Inventors:
CIVELLI, Olivier; US
VAN TOL, Hubert; CA
Agent:
McDONNELL, John, M.; Allegretti & Witcoff Ten South Wacker Drive Chicago, IL 60606, US
NOONAN, Kevin, E.; Allegretti & Witcoff, Ltd Ten South Wacker Drive Chicago, IL 60606, US
Priority Data:
626,61807.12.1990US
Title (EN) HUMAN DOPAMINE D4 RECEPTOR AND ITS USES
(FR) RECEPTEUR DOPAMINERGIQUE D4 HUMAIN ET SES UTILISATIONS
Abstract:
(EN) The present invention is directed toward the isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor is provided by the invention. The invention also includes a recombinant eukaryotic expression vector capable of expressing the human D4 dopamine receptor in cultures of transformed eukaryotic cells and such cultures of transformed eukaryotic cells which synthesize the human D4 dopamine receptor.
(FR) La présente invention se rapporte à l'isolement, la caractérisation et l'utilisation pharmacologique du récepteur dopaminergique (D4) humain. La séquence nucléotidique du gène correspondant à ce récepteur est décrite. L'invention se rapporte aussi à un vecteur d'expression eucaryote de recombinaison pouvant exprimer le récepteur dopaminergique D4 humain dans des cultures de cellules eucaryotes transformées et à de telles cultures de cellules eucaryotes transformées qui synthétisent le récepteur dopaminergique D4 humain.
Designated States: AU, CA, FI, JP, NO
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, MC, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI932573NO19932057EP0574406JPH06503958CA2097698AU1991091403