Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1992010509) RENIN-INHIBITING PEPTIDES OF THE CYCLOHEXYLSTATIN TYPE, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN MEDICAMENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/010509 International Application No.: PCT/EP1991/002300
Publication Date: 25.06.1992 International Filing Date: 03.12.1991
Chapter 2 Demand Filed: 03.12.1991
IPC:
A61K 38/00 (2006.01) ,C07D 339/06 (2006.01) ,C07D 409/12 (2006.01) ,C07D 409/14 (2006.01) ,C07K 5/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
339
Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
02
Five-membered rings
06
having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
409
Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
409
Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
14
containing three or more hetero rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
02
containing at least one abnormal peptide link
Applicants:
BAYER AKTIENGESELLSCHAFT [DE/DE]; D-51368 Leverkusen, DE (AllExceptUS)
BENDER, Wolfgang [DE/DE]; DE (UsOnly)
SCHMIDT, Gunter [DE/DE]; DE (UsOnly)
KNORR, Andreas [DE/DE]; DE (UsOnly)
STASCH, Johannes-Peter [DE/DE]; DE (UsOnly)
Inventors:
BENDER, Wolfgang; DE
SCHMIDT, Gunter; DE
KNORR, Andreas; DE
STASCH, Johannes-Peter; DE
Priority Data:
P 40 38 921.906.12.1990DE
Title (DE) RENININHIBITORISCHE PEPTIDE VOM CYCLOHEXYLSTATIN-TYP, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG IN ARZNEIMITTELN
(EN) RENIN-INHIBITING PEPTIDES OF THE CYCLOHEXYLSTATIN TYPE, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN MEDICAMENTS
(FR) PEPTIDES INHIBITEURS DE LA RENINE DU TYPE DE LA CYCLOHEXYLSTATINE, LEUR PROCEDE DE PRODUCTION ET LEUR UTILISATION DANS DES MEDICAMENTS
Abstract:
(DE) Die vorliegende Erfindung betrifft renininhibitorische Peptide vom Cyclohexylstatin-Typ der allgemeinen Formel (I), in welcher A, B, D, E, Y, R1, R2 und n die in der Beschreibung angegebene Bedeutung haben, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln, insbesondere in kreislaufbeeinflussenden Arzneimitteln.
(EN) Renin-inhibiting peptides of the cyclohexylstatin type having general formula (I), in which A, B, D, E, Y, R1, R2 and n have the meanings given in the description, are disclosed, as well as a process for producing the same and their use in medicaments, in particular medicaments that influence blood circulation.
(FR) L'invention concerne des peptides inhibiteurs de la rénine du type de la cyclohexylstatine ayant la formule générale (I), dans laquelle A, B, D, E, Y, R1, R2 et n ont la notation donnée dans la description, leur procédé de production et leur utilisation dans des médicaments, notamment dans des médicaments ayant un effet sur la circulation sanguine.
Designated States: AU, BG, BR, CA, CS, FI, HU, JP, KR, NO, PL, RO, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, MC, NL, SE)
Publication Language: German (DE)
Filing Language: German (DE)
Also published as:
JPH06503315AU1991090252