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1. (WO1992010169) METHOD FOR THE MANUFACTURE OF A CONTROLLED RELEASE SOLID UNIT DOSAGE FORM
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/010169 International Application No.: PCT/SE1991/000813
Publication Date: 25.06.1992 International Filing Date: 03.12.1991
Chapter 2 Demand Filed: 03.06.1992
IPC:
A61K 9/16 (2006.01) ,A61K 9/20 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
Applicants:
AKTIEBOLAGET ASTRA [SE/SE]; S-151 85 Södertälje, SE
Inventors:
LUNDBERG, Per, Johan, Gunnar; SE
Agent:
DANIELSSON, Stern ; AB Astra Patent Department S-151 85 Södertälje, SE
Priority Data:
9003904-107.12.1990SE
Title (EN) METHOD FOR THE MANUFACTURE OF A CONTROLLED RELEASE SOLID UNIT DOSAGE FORM
(FR) PROCEDE DE FABRICATION D'UNE UNITE DE DOSAGE SOLIDE A LIBERATION CONTROLEE
Abstract:
(EN) A method for the manufacture of oral controlled release dosage units containing hydroxypropyl methylcellulose wherein the aqueous granulation is performed in the presence of one or more solutes, which inhibit gel formation during the granulation but allows the formation of a gel when administered orally. Also the new dosage units prepared according to the invention are included.
(FR) Procédé de fabrication d'unités de dosage orales à libération contrôlée contenant de la méthylcellulose hydroxypropyle, dans lequel la granulation aqueuse s'effectue en présence d'un ou plusieurs solutés empêchant la formation de gel pendant la granulation mais permettant la formation d'un gel, dans le cas d'une administration orale. L'invention décrit également les nouvelles unités de dosage préparées au moyen du procédé.
Designated States: AT, AU, BB, BG, BR, CA, CH, CS, DE, DK, ES, FI, GB, HU, JP, KP, KR, LK, LU, MG, MW, NL, NO, PL, RO, SD, SE, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, MC, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI932552NO19932054ES2079689EP0560822US5419918JP3239319
JPH06503310DE000069114721PT99721AU1991089309DK0560822