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1. (WO1992009701) ANALYTICAL TRACERS FOR CANCER, PARTICULARLY MALIGNANT BREAST CANCER
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/009701 International Application No.: PCT/FR1991/000924
Publication Date: 11.06.1992 International Filing Date: 21.11.1991
IPC:
A61K 38/00 (2006.01) ,C12N 9/64 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
48
acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
50
Proteinases
64
derived from animal tissue, e.g. rennin
Applicants:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) [FR/FR]; 101, rue de Tolbiac F-75654 Paris Cédex 13, FR
Inventors:
BASSET, Paul; FR
BELLOCQ, Jean-Pierre; FR
CHAMBON, Pierre; FR
Agent:
CABINET MALEMONT; 42, avenue du Président-Wilson F-75116 Paris, FR
Priority Data:
9025326.121.11.1990GB
Title (EN) ANALYTICAL TRACERS FOR CANCER, PARTICULARLY MALIGNANT BREAST CANCER
(FR) MARQUEURS ANALYTIQUES POUR LE CANCER, NOTAMMENT POUR LE CANCER MALIN DU SEIN
Abstract:
(EN) A gene is provided which codes for a new member of the metalloproteinase family which has been discovered to be specifically linked to invasive breast cancer. Also provided are methods for diagnosing said cancer by detecting the tracer or its nucleotide sequence, and treatment or prevention by inhibiting or modifying the activity or binding of the tracer, or disrupting its synthesis.
(FR) La présente invention porte sur un gène codant pour un nouvel élément de la famille des métalloprotéinases qui a été découvert comme étant spécifiquement associé au cancer du sein invasif, ainsi que sur des procédés de diagnostic pour un tel cancer comprenant la détection du marqueur ou de sa séquence nucléotidique, et sur le traitement ou la prophylaxie par inhibition, modification de l'activité ou liaison du marqueur, ou par perturbation de sa synthèse.
Designated States: AU, CA, HU, JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
ES2101079EP0513316US5236844US5484726JP3516448JPH05505530
CA2073860DE000069125824PT99562GB2250993AU1991090896DK0513316