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1. (WO1992009688) MICE HAVING $g(b)2 MICROGLOBULIN GENE DISRUPTION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/009688 International Application No.: PCT/US1991/008680
Publication Date: 11.06.1992 International Filing Date: 21.11.1991
Chapter 2 Demand Filed: 18.06.1992
IPC:
A61K 48/00 (2006.01) ,C12N 15/85 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
Applicants:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massachusetts Avenue Cambridge, MA 02139, US
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH [US/US]; Nine Cambridge Center Cambridge, MA 02142, US
Inventors:
ZIJLSTRA, Maarten; US
BIX, Mark; US
JAENISCH, Rudolf; US
RAULET, David, H.; US
Agent:
GRANAHAN, Patricia ; Hamilton, Brook, Smith & Reynolds Two Militia Drive Lexington, MA 02139, US
Priority Data:
616,58521.11.1990US
Title (EN) MICE HAVING $g(b)2 MICROGLOBULIN GENE DISRUPTION
(FR) SOURIS A DISLOCATION DE GENE DE MICROGLOBULINE $g(b)2
Abstract:
(EN) Mice heterozygous (+/-) or homozygous (-/-) for a $g(b)2-microglobulin gene disruption; a method of producing tissues which are heterozygous (+/-) or homozygous (-/-) for a $g(b)2-microglobulin disruption; tissues produced by the method; and uses therefor.
(FR) Souris hétérozygotes (+/-) ou homozygotes (-/-) à dislocation de gène de microglobuline $g(b)2; procédé de production de tissus hétérozygotes (+/-) ou homozygotes (-/-) à dislocation de microglobuline $g(b)2; tissus produits au moyen du procédé; utilisations desdits tissus.
Designated States: AU, CA, JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1991090761