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1. (WO1992009573) CYCLOPENTANE ETHER DERIVATIVES, METHODS FOR PREPARING THEM AND THEIR USE IN PHARMACEUTICALS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/009573 International Application No.: PCT/DE1991/000925
Publication Date: 11.06.1992 International Filing Date: 23.11.1991
Chapter 2 Demand Filed: 11.06.1992
IPC:
C07C 405/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
405
Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins
Applicants:
SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN [DE/DE]; Müllerstr. 170/178 Postfach 65 03 11 D-13342 Berlin, DE (AllExceptUS)
REHWINKEL, Hartmut [DE/DE]; DE (UsOnly)
KLAR, Ulrich [DE/DE]; DE (UsOnly)
VORBRÜGGEN, Helmut [DE/DE]; DE (UsOnly)
THIERAUCH, Karl-Heinz [DE/DE]; DE (UsOnly)
VERHALLEN, Peter [NL/DE]; DE (UsOnly)
Inventors:
REHWINKEL, Hartmut; DE
KLAR, Ulrich; DE
VORBRÜGGEN, Helmut; DE
THIERAUCH, Karl-Heinz; DE
VERHALLEN, Peter; DE
Priority Data:
P 40 37 941.823.11.1990DE
Title (DE) CYCLOPENTANETHERDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE PHARMAZEUTISCHE VERWENDUNG
(EN) CYCLOPENTANE ETHER DERIVATIVES, METHODS FOR PREPARING THEM AND THEIR USE IN PHARMACEUTICALS
(FR) DERIVES D'ETHER DE CYCLOPENTANE, PROCEDE POUR LEUR FABRICATION ET LEUR APPLICATION PHARMACEUTIQUE
Abstract:
(DE) Die Erfindung betrifft Cyclopentanether-Derivate der Formel (I), deren Salze mit physiologisch verträglichen Basen, sowie die $g(a)-, $g(b)- oder $g(g)-Cyclodextrinclathrate, sowie die mit Liposomen verkapselten Verbindungen der Formel (I), Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung.
(EN) The invention concerns cyclopentane ether derivatives of formula (I), their salts with physiologically tolerable bases, as well as the $g(a), $g(b)- and $g(g)-cyclodextrin clathrates and compounds of formula (I) encapsulated with liposomes. The invention also concerns methods for preparing these compounds and their use in pharmaceuticals.
(FR) La présente invention se rapporte à des dérivés d'éther de cyclopentane de formule (I), à leurs sels avec des bases physiologiquement tolérables, ainsi qu'aux clathrates de $g(a), $g(b) ou $g(g)-cyclodextrine, aux composés encapsulés avec des liposomes de formule (I), et au procédé pour leur fabrication et leur utilisation pharmaceutique.
Designated States: AU, CA, HU, JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: German (DE)
Filing Language: German (DE)
Also published as:
EP0558570ES2086005US5625067JPH06506439CA2096848PT99586
AU1991089463DK0558570