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1. (WO1992009301) TISSUE SEALANT AND GROWTH FACTOR CONTAINING COMPOSITIONS THAT PROMOTE ACCELERATED WOUND HEALING
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/009301 International Application No.: PCT/US1991/008869
Publication Date: 11.06.1992 International Filing Date: 27.11.1991
Chapter 2 Demand Filed: 26.06.1992
IPC:
A61K 38/00 (2006.01) ,A61K 31/715 (2006.01) ,A61K 38/17 (2006.01) ,A61K 38/18 (2006.01) ,A61K 38/22 (2006.01) ,A61K 38/27 (2006.01) ,A61K 38/36 (2006.01) ,A61L 15/32 (2006.01) ,A61L 24/00 (2006.01) ,A61L 24/10 (2006.01) ,A61L 26/00 (2006.01) ,A61P 17/00 (2006.01) ,A61P 43/00 (2006.01) ,C07K 14/50 (2006.01) ,C12N 5/071 (2010.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
715
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
27
Growth hormone (GH) (Somatotropin)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
36
Blood coagulation or fibrinolysis factors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15
Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16
Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
22
containing macromolecular materials
32
Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24
Surgical adhesives or cements; Adhesives for colostomy devices
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24
Surgical adhesives or cements; Adhesives for colostomy devices
04
containing macromolecular materials
10
Polypeptides; Proteins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
26
Chemical aspects of, or use of materials for, liquid bandages
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
475
Growth factors; Growth regulators
50
Fibroblast growth factor (FGF)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
Applicants:
THE AMERICAN NATIONAL RED CROSS [US/US]; 430 17th Street, N.W. Washington, DC 20006, US
GREISLER, Howard, P. [US/US]; US
Inventors:
GREISLER, Howard, P.; US
NUNEZ, Hernan, A.; US
DROHAN, William, N.; US
BURGESS, Wilson, H.; US
MACIAG, Thomas; US
Agent:
STERNE, Robert, Greene ; Sterne, Kessler, Goldstein & Fox 1225 Connecticut Avenue, N.W. Suite 300 Washington, DC 20036, US
GOLDSTEIN, Jorge, A.; Sterne, Kessler, Goldstein & Fox 1225 Connecticut Avenue, N.W. Suite 300 Washington, D.C. 20036, US
Priority Data:
618,41927.11.1990US
Title (EN) TISSUE SEALANT AND GROWTH FACTOR CONTAINING COMPOSITIONS THAT PROMOTE ACCELERATED WOUND HEALING
(FR) COMPOSITIONS CONTENANT UN AGENT DE FERMETURE DES TISSUS ET DES FACTEURS DE CROISSANCE, QUI ACCELERENT LA CICATRISATION
Abstract:
(EN) This invention provides a growth factor-supplemented tissue sealant and methods for using said sealant to promote wound healing, endothelialization of vascular protheses, and the $i(in vitro) proliferation and differentiation of animal cells. In particular, this invention provides fibrin glue that is supplemented with at least one growth factor, such as a heparin binding growth factor and/or bone morphogenic proteins. The particular growth factor or factors selected is a function of its use.
(FR) Cette invention propose un agent de fermeture des tissus complété par un facteur de croissance et des procédés pour utiliser ledit agent de fermeture des tissus afin d'accélérer la cicatrisation, l'endothélialisation de prothèses vasculaires, et la prolifération ainsi que la différenciation $i(in vitro) de cellules animales. Cette invention propose en particulier une colle de fibrine qui est complétée avec au moins un facteur de croissance tel qu'un facteur de croissance se liant à l'héparine et/ou des protéines morphogéniques osseuses. Le facteur ou les facteurs de croissance sont sélectionnés en fonction de l'utilisation prévue.
Designated States: AU, BB, BG, BR, CA, CS, FI, HU, JP, KP, KR, LK, MC, MG, MN, MW, NO, PL, RO, SD, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0564502JP3604688JPH06506191CA2097063AU1991091093DK0564502