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1. (WO1992009277) NUTRIENT SUPPLY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/009277 International Application No.: PCT/SE1991/000810
Publication Date: 11.06.1992 International Filing Date: 28.11.1991
Chapter 2 Demand Filed: 05.06.1992
IPC:
A23L 1/305 (2006.01) ,A61K 9/00 (2006.01) ,A61K 31/19 (2006.01) ,A61K 31/195 (2006.01) ,A61K 38/05 (2006.01)
A HUMAN NECESSITIES
23
FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1
Foods or foodstuffs; Their preparation or treatment
29
Modifying nutritive qualities of foods; Dietetic products
30
containing additives
305
Amino acids, peptides or proteins 
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
05
Dipeptides
Applicants:
KABI PHARMACIA AB [SE/SE]; S-751 82 Uppsala, SE (AllExceptUS)
KIHLBERG, Reinhold [SE/SE]; SE (UsOnly)
NORRLIND, Björn [SE/SE]; SE (UsOnly)
Inventors:
KIHLBERG, Reinhold; SE
NORRLIND, Björn; SE
Agent:
TANNERFELDT, Agneta; Kabi Pharmacia AB S-112 87 Stockholm, SE
Priority Data:
9003844-903.12.1990SE
Title (EN) NUTRIENT SUPPLY
(FR) SOURCE NUTRITIVE
Abstract:
(EN) The invention relates to a composition for oral or parenteral use, characterized in that the composition contains free L-glutamine and also at least one derivative of L-glutamine and optionally at least one precursor to L-glutamine, the composition being prepared aseptically and freeze-dried in powder form and radiation-sterilized, or in the form of a solution which is stored at low temperature, preferably in deep-frozen form. The derivative preferably consists of peptides, such as glycyl-L-glutamine and/or L-alanyl-L-glutamine, and the precursor may consist of alpha-keto-glutaric acid or the salt/derivative thereof. The derivative may also consist of N-acetyl-L-glutamine. The composition may also contain other nutrient components, or technical auxiliary substances, such as carbohydrates, sugar alcohols, vitamins and/or amino acids, preferably in freeze-dried form. The invention also relates to the production of the composition and to a method of preparing a nutrient solution.
(FR) On décrit une composition pour administration par voie orale ou parentérale, caractérisée en ce que la composition contient de la L-glutamine libre et au moins un dérivé de L-glutamine et éventuellement au moins un précurseur de L-glutamine, la composition étant préparée dans des conditions aseptiques et étant lyophilisée sous forme de poudre et stérilisée par radiations, ou sous forme d'une solution stockée à basse température, de préférence surgelée. Le dérivé est de préférence constituée par des peptides, par exemple la glycyl-L-glutamine et/ou la L-alanyl-L-glutamine, et le précurseur peut comprendre l'acide alpha-cétoglutarique ou le sel/dérivé de celui-ci. Le dérivé peut également comprendre de la N-acétyl-L-glutamine. La composition peut aussi contenir d'autres constituants nutritifs ou des substances techniques auxiliaires, par exemple des hydrates de carbone, des alcools de sucres, des vitamines et/ou des acides aminés, de préférence sous une forme lyophilisée. L'invention concerne également la production de ladite composition et un procédé de préparation d'une solution nutritive.
Designated States: AU, CA, FI, JP, NO, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1991089313