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1. WO1992008460 - BIS-DIOXOPIPERAZINES FOR TREATING LIVER TUMOURS

Publication Number WO/1992/008460
Publication Date 29.05.1992
International Application No. PCT/GB1991/002018
International Filing Date 15.11.1991
Chapter 2 Demand Filed 15.05.1992
IPC
A61K 31/495 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
CPC
A61K 31/495
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
Applicants
  • WINDLESHAW ENTERPRISES LIMITED [GB]/[GB] (AllExceptUS)
  • HELLMANN, Kurt [GB]/[GB] (UsOnly)
Inventors
  • HELLMANN, Kurt
Agents
  • JUMP, Timothy, John, Simon
Priority Data
9024861.815.11.1990GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BIS-DIOXOPIPERAZINES FOR TREATING LIVER TUMOURS
(FR) BIS-DIOXOPIPERAZINES POUR TRAITER LES TUMEURS DU FOIE
Abstract
(EN)
A compound for use in a treatment for liver tumours, preferably in combination with radiation therapy, characterised by comprising a bis(3,5-dioxopiperazine-1-yl)alkane of general formula (I); where R1 is not the same as R2 and R1 and R2 are hydrogen, or alkyl with 1-4 carbon atoms.
(FR)
Composition destinée à être utilisée dans un traitement pour les tumeurs du foie, de préférence en association avec une thérapie par les rayonnements, se caractérisant par le fait qu'elle comprend un bis(3,5-dioxopiperazine-1-yle) alcane représenté par la formule générale (I): dans laquelle R1 est différent de R2, et dans laquelle R1 et R2 sont hydrogène, ou alkyle comprenant de 1 à 4 atomes de carbone.
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