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Machine translation
1. (WO1992003552) $i(P. FALCIPARUM)-INFECTED RED CORPUSCLES AND IMMUNOGENIC COMPOSITIONS CONTAINING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1992/003552    International Application No.:    PCT/FR1991/000667
Publication Date: 05.03.1992 International Filing Date: 14.08.1991
Chapter 2 Demand Filed:    24.02.1992    
IPC:
A61K 39/00 (2006.01), C07K 14/445 (2006.01), C07K 16/20 (2006.01)
Applicants: INSTITUT PASTEUR [FR/FR]; 25-28, rue du Dr.-Roux, F-75724 Paris Cédex 15 (FR) (For All Designated States Except US).
MULLER-HILL, Benno [DE/DE]; (DE) (For US Only).
KUN, Jurgen [DE/DE]; (DE) (For US Only).
SCHREIBER, Michael [DE/DE]; (DE) (For US Only).
GYSIN, Jurg [FR/FR]; (FR) (For US Only).
PEREIRA DA SILVA, Luiz [BR/FR]; (FR) (For US Only).
BRETON, Catherine [FR/FR]; (FR) (For US Only)
Inventors: MULLER-HILL, Benno; (DE).
KUN, Jurgen; (DE).
SCHREIBER, Michael; (DE).
GYSIN, Jurg; (FR).
PEREIRA DA SILVA, Luiz; (FR).
BRETON, Catherine; (FR)
Agent: GUTMANN, Ernest; Ernest Gutmann-Yves Plasseraud S.A., 67, bld. Haussmann, F-75008 Paris (FR)
Priority Data:
90/10363 14.08.1990 FR
Title (EN) $i(P. FALCIPARUM)-INFECTED RED CORPUSCLES AND IMMUNOGENIC COMPOSITIONS CONTAINING SAME
(FR) POLYPEPTIDES DE SURFACE DE GLOBULES ROUGES INFECTES PAR $i(P. FALCIPARUM) ET COMPOSITIONS IMMUNOGENES LES CONTENANT
Abstract: front page image
(EN)Polypeptides capable of including in vivo protective antibodies against $i(P. falciparum), said antibodies being capable of a mediatory function on the phagocytose of $i(P. falciparum)-infected red corpuscles. The invention also concerns the used of said polypeptides or antibodies, especially of the monoclonal kind, recognizing these polypeptides, for carrying out in vitro methods of diagnosing paludism. Furthermore it aims to create polypeptide-based compositions which could lead to the production of vaccines.
(FR)L'invention a pour objet des polypeptides susceptibles d'induire $i(in vivo) des anticorps protecteurs, contre $i(P. falciparum), ces anticorps étant susceptibles d'exercer une fonction de médiation de la phagocytose des globules rouges infectés par $i(P. falciparum). L'invention concerne également l'utilisation de ces polypeptides, ou des anticorps, notamment monoclonaux, reconnaissant ces polypeptides, pour la mise en ÷uvre de méthodes de diagnostic $i(in vitro) du paludisme. L'invention vise également des compositions de vaccins à base de ces polypeptides.
Designated States: CA, JP, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE).
Publication Language: French (FR)
Filing Language: French (FR)