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Machine translation
1. (WO1992000313) TRICYCLO COMPOUNDS, A PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1992/000313    International Application No.:    PCT/JP1991/000811
Publication Date: 09.01.1992 International Filing Date: 18.06.1991
Chapter 2 Demand Filed:    23.01.1992    
IPC:
C07H 19/01 (2006.01)
Applicants: FUJISAWA PHARMACEUTICAL CO., LTD. [JP/JP]; 4-7, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 541 (JP) (For All Designated States Except US).
KASAHARA, Chiyoshi [JP/JP]; (JP) (For US Only).
OHKAWA, Takehiko [JP/JP]; (JP) (For US Only).
HASHIMOTO, Masashi [JP/JP]; (JP) (For US Only)
Inventors: KASAHARA, Chiyoshi; (JP).
OHKAWA, Takehiko; (JP).
HASHIMOTO, Masashi; (JP)
Agent: UEKI, Kyuichi; Ueki & Co. Room 407, Shinko Bldg., 3-7, Dojima 2-chome, Kita-ku, Osaka-shi, Osaka 530 (JP)
Priority Data:
9014136.7 25.06.1990 GB
Title (EN) TRICYCLO COMPOUNDS, A PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
(FR) COMPOSES TRICYCLO, LEUR PROCEDE DE PRODUCTION ET COMPOSITION PHARMACEUTIQUE CONTENANT CES COMPOSES
Abstract: front page image
(EN)Compounds of formula (I) are disclosed, wherein R?1¿ is hydrogen or acyl, R?2¿ is hydrogen, hydroxy, alkoxy or acyloxy, R?3¿ is (C¿3?-C¿7?)alkyl, aryl(C¿2?-C¿7?)alkyl, protected carboxy(C¿2?-C¿7?)alkyl, 1-(C¿3?-C¿7?)alkenyl, aryl-1-(C¿2?-C¿7?)alkenyl or protected carboxy-1-(C¿2?-C¿7?)alkenyl, R?4¿ is hydroxy or alkoxy, R?5¿ is hydrogen and R?6¿ is hydroxy or methoxy, or R?5¿ and R?6¿ are combined to form oxo, A is methylene, hydroxymethylene or carbonyl, n is an integer of 1 or 2, and the symbol of a line and dotted line is a single bond or a double bond and salts thereof. And processes for their production, and pharmaceutical compositions containing them are also described.
(FR)L'invention concerne des composés de la formule (I), dans laquelle R?1¿ représente hydrogène ou acyle, R?2¿ représente hydrogène, hydroxy, alcoxy ou acyloxy, R?3¿ est (C¿3?-C¿7?)alkyle, aryl(C¿2?-C¿7?), carboxy(C¿2?-C¿7?)alkyle protégé, 1-(C¿3?-C¿7?)alcényle, aryl-1-(C¿2?-C¿7?)alcényle, R?4¿ représente hydroxy ou alcoxy, R?5¿ représente hydrogène et R?6¿ est hydroxy ou méthoxy ou bien R?5¿ et R?6¿ sont combinés pour former oxo, A représente méthylène, hydroxyméthylène ou carbonyle, n est un nombre entier valant 1 ou 2, et le symbole constitué d'une ligne et d'une ligne en pointillé représente une liaison simple ou double. L'invention concerne aussi des sels de ces composés, des procédés de production desdits composés ainsi que des compositions pharmaceutiques contenant ces composés.
Designated States: JP, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE).
Publication Language: English (EN)
Filing Language: English (EN)