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Machine translation
1. (WO1992000294) NAPHTHOTHIOPYRANONE DERIVATIVE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1992/000294    International Application No.:    PCT/JP1991/000825
Publication Date: 09.01.1992 International Filing Date: 20.06.1991
Chapter 2 Demand Filed:    14.01.1992    
IPC:
C07D 335/08 (2006.01), C07D 409/06 (2006.01), C07D 521/00 (2006.01)
Applicants: TAISHO PHARMACEUTICAL CO., LTD. [JP/JP]; 24-1, Takada 3-chome, Toshima-ku, Tokyo 171 (JP) (For All Designated States Except US).
SANO, Tatsuhiko [JP/JP]; (JP) (For US Only).
SAIJO, Keiko [JP/JP]; (JP) (For US Only).
YOKOMORI, Sadakazu [JP/JP]; (JP) (For US Only).
NAKASHIMA, Yoshimoto [JP/JP]; (JP) (For US Only).
HATAYAMA, Katsuo [JP/JP]; (JP) (For US Only)
Inventors: SANO, Tatsuhiko; (JP).
SAIJO, Keiko; (JP).
YOKOMORI, Sadakazu; (JP).
NAKASHIMA, Yoshimoto; (JP).
HATAYAMA, Katsuo; (JP)
Agent: KITAGAWA, Tomizou; Taisho Pharmaceutical Co., Ltd., 24-1, Takada 3-chome, Toshima-ku, Tokyo 171 (JP)
Priority Data:
2/164658 22.06.1990 JP
Title (EN) NAPHTHOTHIOPYRANONE DERIVATIVE
(FR) DERIVE DE NAPHTOTHIOPYRANONE
Abstract: front page image
(EN)A naphthothiopyranone derivative of general formula (I) or an acid addition salt thereof, wherein R?1¿ represents hydrogen or C¿1? to C¿4? alkyl. It has a more excellent serotonin 3 receptor antagonism than that of conventional compounds and various actions based thereon, e.g., an antiemetic action, an action of regulating gastrointestinal movement, and an antianxiety action.
(FR)Dérivé de naphtothiopyranone de formule générale (I) ou sel d'addition d'acide de ce dérivé. Dans la formule, R?1¿ représente hydrogène ou alkyle C¿1?-C¿4?. Ce composé présente un meilleur effet d'antagonisme vis-à-vis du récepteur de sérotonine 3 que les composés habituels, ainsi que des caractéristiques relatives, à savoir une action antiémétique, une action de régulation des mouvements gastro-intestinaux et une action anxiolytique.
Designated States: CA, JP, KR, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)