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1. WO1992000088 - BILE ACID SECRETAGOGUE

Publication Number WO/1992/000088
Publication Date 09.01.1992
International Application No. PCT/JP1991/000848
International Filing Date 24.06.1991
Chapter 2 Demand Filed 22.10.1991
IPC
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 38/17 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
C12N 9/64 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
48acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
50Proteinases
64derived from animal tissue, e.g. rennin
C12N 9/66 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
48acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
66Elastase
CPC
A61K 38/1709
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
1703from vertebrates
1709from mammals
C12N 9/6421
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
14Hydrolases (3)
48acting on peptide bonds (3.4)
50Proteinases ; , e.g. Endopeptidases (3.4.21-3.4.25)
64derived from animal tissue
6421from mammals
C12N 9/6448
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
14Hydrolases (3)
48acting on peptide bonds (3.4)
50Proteinases ; , e.g. Endopeptidases (3.4.21-3.4.25)
64derived from animal tissue
6421from mammals
6424Serine endopeptidases (3.4.21)
6448Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
Applicants
  • SANKYO COMPANY, LIMITED [JP]/[JP] (AllExceptUS)
  • TAKIGUCHI, Yo [JP]/[JP] (UsOnly)
Inventors
  • TAKIGUCHI, Yo
Agents
  • NAKAMURA, Minoru
Priority Data
2/17201628.06.1990JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) BILE ACID SECRETAGOGUE
(FR) SECRETAGOGUE D'ACIDE BILIAIRE
Abstract
(EN) A bile acid secretagogue comprising as an active ingredient a protein with an amino acid sequence which is common to human elastase IIIB, human protease E of a molecular species, human elastase IIIA, human protease E of another molecular species, and subunit III of bovine procarboxypeptidase A. It has an excellent effect of stimulating secretion of bile acid and is effective in preventing and treating arteriosclerosis.
(FR) Un secrétagogue d'acide biliaire contient en tant qu'ingrédient actif une protéine ayant une séquence d'acides aminés commune à l'élastase humaine IIIB, à la protéase humaine E d'une espèce moléculaire, à l'élastase humaine IIIA, à la protéase humaine E d'une autre espèce moléculaire, et à la sous-unité III de la procarboxypeptidase bovine A. Ce secrétagogue stimule de manière excellente la sécrétion de l'acide biliaire et est utile pour prévenir et traiter l'artériosclérose.
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