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1. (WO1992000081) VACCINE COMPOSITIONS CONTAINING LIPOSOMES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1992/000081 International Application No.: PCT/US1991/004532
Publication Date: 09.01.1992 International Filing Date: 25.06.1991
Chapter 2 Demand Filed: 21.01.1992
IPC:
A61K 9/00 (2006.01) ,A61K 9/127 (2006.01) ,A61K 39/015 (2006.01) ,A61K 39/145 (2006.01) ,A61K 39/21 (2006.01) ,A61K 39/245 (2006.01) ,A61K 39/39 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
002
Protozoa antigens
015
Hemosporidia antigens, e.g. Plasmodium antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
145
Orthomyxoviridae, e.g. influenza virus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
21
Retroviridae, e.g. equine infectious anemia virus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
245
Herpetoviridae, e.g. herpes simplex virus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
Applicants:
CHIRON CORPORATION [US/US]; 4560 Horton Street Emeryville, CA 94608-2916, US
Inventors:
BARCHFELD, Gail, L.; US
OTT, Gary; US
VAN NEST, Gary, A.; US
Agent:
NEELEY, Richard, L. ; Cooley Godward Castro Huddleson & Tatum Five Palo Alto Square 4th Floor Palo Alto, CA 94306, US
Priority Data:
546,58529.06.1990US
Title (EN) VACCINE COMPOSITIONS CONTAINING LIPOSOMES
(FR) COMPOSITIONS DE VACCINS CONTENANT DES LIPOSOMES
Abstract:
(EN) A vaccine composition, comprising an antigenic substance in association with a liposome and an oil-in-water emulsion comprising a muramyl peptide, a metabolizable oil, and optionally an additional emulsifying agent. The two components of the adjuvant (i.e., the liposome/antigen component and the emulsion component) act together to produce high levels of immune response.
(FR) Composition de vaccin, comprenant une substance antigénique en association avec un liposome et une émulsion huile-dans-l'eau composée d'un peptide muramyle, d'une huile métabolisable, et éventuellement d'un agent émulsifiant supplémentaire. Les deux composants de l'adjuvant (c'est-à-dire le composant liposome/antigène et le composant émulsion) interagissent et produisent des niveaux de réponse immunitaire élevés.
Designated States: AU, BB, BG, BR, CA, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, PL, RO, SD, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI925835NO19924858EP0489153JP2502234JPH06504759CA2086094
DE000069131709PT98156AU1991083230