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1. (WO1991018992) METHODS TO MAKE AND USE PROTEINACEOUS MATERIAL PRESENT IN KININ-FREE HIGH MOLECULAR WEIGHT KININOGEN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/018992 International Application No.: PCT/US1991/003956
Publication Date: 12.12.1991 International Filing Date: 05.06.1991
IPC:
A61L 33/12 (2006.01) ,C07K 7/18 (2006.01) ,C12N 5/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
33
Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
06
Use of macromolecular materials
12
Polypeptides, proteins or derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
18
Kallidins; Bradykinins; Related peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
Applicants:
WISCONSIN ALUMNI RESEARCH FOUNDATION [US/US]; 614 North Walnut Street Madison, WI 53705, US
Inventors:
MOSHER, Deane, F.; US
ASAKURA, Shinji; US
Agent:
SCHWARTZ, Carl, R. ; Quarles & Brady 411 East Wisconsin Avenue Milwaukee, WI 53202-4497, US
Priority Data:
544,13308.06.1990US
Title (EN) METHODS TO MAKE AND USE PROTEINACEOUS MATERIAL PRESENT IN KININ-FREE HIGH MOLECULAR WEIGHT KININOGEN
(FR) PROCEDES DE FABRICATION ET D'UTILISATION DE MATIERE PROTEIQUE PRESENTE DANS LE KININOGENE DE MASSE MOLECULAIRE ELEVEE EXEMPT DE KININE
Abstract:
(EN) Disclosed herein are methods for using a proteinaceous material present in kinin-free high molecular weight kininogen to treat surfaces to prevent or minimize adhesion by blood components and/or animal cells. For example, in medical applications, one can treat plastic tubes or other conduits that carry blood to reduce the tendency of the blood to block the conduit. Also disclosed is an improved method of purifying kinin-free high molecular weight kininogen.
(FR) Procédés d'utilisation d'une matière protéique présente dans un kininogène de masse moléculaire élevée exempt de kinine afin de traiter des surfaces de manière à empêcher ou à réduire au minimum l'adhérence par des composants du sang et/ou des cellules animales. Par exemple, on peut traiter dans des applications médicales des tubes plastiques ou d'autres conduits transportant du sang, afin de réduire la tendance du sang à bloquer le conduit. L'invention concerne également un procédé amélioré de purification de kininogène de masse moléculaire élevée exempt de kinine.
Designated States: AU, CA, JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)