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1. (WO1991018107) MEASURING NON-DYSTROPHIN PROTEINS AND DIAGNOSING MUSCULAR DYSTROPHY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/018107 International Application No.: PCT/US1991/003632
Publication Date: 28.11.1991 International Filing Date: 23.05.1991
Chapter 2 Demand Filed: 19.12.1991
IPC:
A61K 38/00 (2006.01) ,A61K 39/00 (2006.01) ,C07K 14/47 (2006.01) ,C07K 14/705 (2006.01) ,C07K 16/18 (2006.01) ,C07K 16/28 (2006.01) ,G01N 33/68 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
UNIVERSITY OF IOWA RESEARCH FOUNDATION [US/US]; 240H Eckstein Medical Research Building Iowa City, IA 52242, US (AllExceptUS)
CAMPBELL, Kevin, P. [US/US]; US (UsOnly)
ERVASTI, James, M. [US/US]; US (UsOnly)
OHLENDIECK, Kay [US/US]; US (UsOnly)
GAVER, Mitchell, G. [US/US]; US (UsOnly)
KAHL, Steven, D. [US/US]; US (UsOnly)
Inventors:
CAMPBELL, Kevin, P.; US
ERVASTI, James, M.; US
OHLENDIECK, Kay; US
GAVER, Mitchell, G.; US
KAHL, Steven, D.; US
Agent:
BROOK, David, E. ; Hamilton, Brook, Smith & Reynolds Two Militia Drive Lexington, MA 02173, US
Priority Data:
527,58323.05.1990US
Title (EN) MEASURING NON-DYSTROPHIN PROTEINS AND DIAGNOSING MUSCULAR DYSTROPHY
(FR) MESURE DE PROTEINES AUTRES QUE LA DYSTROPHINE ET DIAGNOSTIC DE DYSTROPHIE MUSCULAIRE
Abstract:
(EN) The invention pertains to the dystrophin-glycoprotein complex of mammalian skeletal muscle and a method of isolating said complex. The components of the complex and methods of separating and isolating said components also pertain to the invention. In addition, the invention further relates to a method of detecting and quantifying the loss of a non-dystrophin component of the dystrophin-glycoprotein complex with said loss being indicative of muscular dystrophy.
(FR) L'invention concerne le complexe dystrophine-glycoprotéine des muscles striés de mammifères et un procédé d'isolement de ce complexe, ainsi que les composants du complexe et des procédés de séparation et d'isolement de ces composants. En outre, l'invention concerne un procédé de détection et de quantification des pertes d'un composant autre que la dystrophine du complexe dystrophine-glycoprotéine, ces pertes constituant une indication de la dystrophie musculaire.
Designated States: AU, CA, JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0533830US5260209US5413910US5449616JPH05508019CA2083598
AU1991080532