Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1991018105) LABELED COMPOUNDS FOR USE IN A DIAGNOSTIC BREATH TEST
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/018105 International Application No.: PCT/US1991/003335
Publication Date: 28.11.1991 International Filing Date: 13.05.1991
Chapter 2 Demand Filed: 09.12.1991
IPC:
A61K 51/12 (2006.01) ,C11B 1/00 (2006.01) ,C12N 1/06 (2006.01) ,C12P 7/64 (2006.01) ,G01N 33/497 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
12
characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
C CHEMISTRY; METALLURGY
11
ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
B
PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
1
Production of fats or fatty oils from raw materials
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
06
Lysis of micro-organisms
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7
Preparation of oxygen-containing organic compounds
64
Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
483
Physical analysis of biological material
497
of gaseous biological material, e.g. breath
Applicants:
MARTEK CORPORATION [US/US]; 6480 Dobbin Road Columbia, MD 21045, US
Inventors:
KYLE, David, John; US
Agent:
FIGG, E., Anthony ; Rothwell, Figg, Ernst & Kurz 555 Thirteenth Street, N.W. Suite 701 East Washington, DC 20004, US
Priority Data:
525,82021.05.1990US
Title (EN) LABELED COMPOUNDS FOR USE IN A DIAGNOSTIC BREATH TEST
(FR) COMPOSES MARQUES UTILISES POUR DES TESTS DIAGNOSTIQUES DE L'HALEINE
Abstract:
(EN) Disclosed is a process for the production of compounds labeled with stable isotopes of carbon. Such compounds are useful in diagnostic breath tests. The process involves the cultivation of microorganisms capable of producing such compounds in appropriately controlled environments such as bioreactors, feeding such microorganisms labeled carbon substrates, inducing the microorganisms to produce the labeled compounds and recovering the compounds therefrom. Also, encompassed by the present invention are perlabeled compounds useful in diagnostic breath tests.
(FR) Procédé servant à produire des composés marqués avec des isotopes stables du carbone. De tels composés sont utiles pour des tests diagnostiques de l'haleine. Le procédé consiste à mettre en culture des microorganismes pouvant produire de tels composés dans des milieux régulés de façon appropriée, tels que des bioréacteurs; à alimenter lesdits microorganismes en substrats marqués au carbone; à induire la production par ces microorganismes de composés marqués; et à récupérer des composés ainsi obtenus. On décrit aussi des composés comportant plusieurs marquages, utiles pour des tests diagnostiques de l'haleine.
Designated States: CA, JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0533775JPH05507275CA2083041