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1. (WO1991017774) INCLUSION COMPOUNDS OF NIMESULIDE WITH CYCLODEXTRINS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/017774 International Application No.: PCT/IT1991/000043
Publication Date: 28.11.1991 International Filing Date: 20.05.1991
Chapter 2 Demand Filed: 06.12.1991
IPC:
A61K 31/63 (2006.01) ,A61K 47/48 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
63
Compounds containing para-N-benzene- sulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonohydrazide
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
Applicants:
BOEHRINGER INGELHEIM ITALIA S.P.A. [IT/IT]; Via Pellicceria, 10 I-Firenze, IT (AllExceptUS)
BIETTI, Giuseppe [IT/IT]; IT (UsOnly)
DUBINI, Enrica [IT/IT]; IT (UsOnly)
MAFFIONE, Grazia [IT/IT]; IT (UsOnly)
VIDI, Aldo [IT/IT]; IT (UsOnly)
Inventors:
BIETTI, Giuseppe; IT
DUBINI, Enrica; IT
MAFFIONE, Grazia; IT
VIDI, Aldo; IT
Agent:
AIMI, Luciano; Società Italiana Brevetti Via Carducci, 8 I-20123 Milano , IT
Priority Data:
20393 A/9022.05.1990IT
Title (EN) INCLUSION COMPOUNDS OF NIMESULIDE WITH CYCLODEXTRINS
(FR) COMPOSES D'INCLUSION DE NIMESULIDE AVEC DES CYCLODEXTRINES
Abstract:
(EN) Inclusion compounds of nimesulide with cyclodextrins, in the molar ratio of nimesulide to cyclodextrin comprised between 1:0.5 and 1:15, which possess high solubility and are more rapidly absorbed and/or better tolerated than nimesulide itself.
(FR) Composés d'inclusion de nimesulide avec des cyclodextrines, selon un rapport molaire entre la nimesulide et la cyclodextrine situé entre 1:0,5 et 1:15, extrêmement solubles, absorbés plus rapidement et/ou mieux tolérés que la nimesulide seule.
Designated States: AU, FI, HU, JP, KR, NO, PL, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI925224NO19924492EP0534995JPH06502842KR1019937000160AU1991078665