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1. (WO1991017757) ANTI-TUMOR AGENTS HAVING REDUCED TOXICITY ON THE BASIS OF CYTOSTATIC AGENTS AND XANTHOGENATES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/017757 International Application No.: PCT/EP1991/000905
Publication Date: 28.11.1991 International Filing Date: 14.05.1991
IPC:
A61K 31/66 (2006.01) ,A61K 38/19 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
66
Phosphorus compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
Applicants:
DEUTSCHES KREBSFORSCHUNGSZENTRUM [DE/DE]; Im Neuenheimer Feld 280 D-6900 Heidelberg, DE (AllExceptUS)
SAUER, Gerhard [DE/DE]; DE (UsOnly)
AMTMANN, Eberhard [DE/DE]; DE (UsOnly)
Inventors:
SAUER, Gerhard; DE
AMTMANN, Eberhard; DE
Agent:
DEUFEL.HERTEL.LEWALD; Isartorplatz 6 D-8000 München 2, DE
Priority Data:
P 40 15 603.615.05.1990DE
P 41 15 559.913.05.1991DE
Title (EN) ANTI-TUMOR AGENTS HAVING REDUCED TOXICITY ON THE BASIS OF CYTOSTATIC AGENTS AND XANTHOGENATES
(FR) AGENTS ANTITUMORAUX AYANT UNE TOXICITE REDUITE ET PRODUITS SUR LA BASE D'AGENTS CYTOSTATIQUES ET DE XANTHOGENATES
Abstract:
(EN) The present invention relates to an anti-tumor agent having a synergistically increased effect on the basis of xanthogenate drug, optionally in the presence of C8-C14 monocarboxylic acid and/or its alkali or ammonium salt and optionally tumor necrosis factor, characterized in that it contains additionally a cytostatic agent on the basis of heavy metal or a phosphamide ester.
(FR) L'invention se rapporte à un agent antitumoral ayant un effet accru du point de vue synergique, qui est produit sur la base de xanthogénates médicamenteux, éventuellement en présence d'acide monocarboxylique C8-C14 et/ou de son alcali ou de son sel d'ammonium et éventuellement d'un facteur de nécrose tumorale, et qui est caractérisé en ce qu'il contient en outre un agent cytostatique à base d'un métal lourd ou un ester de phosphamide.
Designated States: AU, CA, HU, JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0482172CA2064067AU1991078707