Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO1991017752) PERCUTANEOUS PREPARATION CONTAINING ESTRADIOL
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/017752 International Application No.: PCT/JP1991/000578
Publication Date: 28.11.1991 International Filing Date: 26.04.1991
IPC:
A61K 9/70 (2006.01) ,A61K 31/565 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
70
Web, sheet or filament bases
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565
not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
Applicants:
HISAMITSU PHARMACEUTICAL CO., INC. [JP/JP]; 408, Tashirodaikanmachi Tosu-shi Saga 841, JP (AllExceptUS)
NAKAGAWA, Akira [JP/JP]; JP (UsOnly)
HIRANO, Munehiko [JP/JP]; JP (UsOnly)
SHINMURA, Miyuki [JP/JP]; JP (UsOnly)
Inventors:
NAKAGAWA, Akira; JP
HIRANO, Munehiko; JP
SHINMURA, Miyuki; JP
Agent:
ITOH, Tetsuya ; Toranomon Denki Bldg. 8-1, Toranomon 2-chome Minato-ku Tokyo 105, JP
Priority Data:
2/12816017.05.1990JP
Title (EN) PERCUTANEOUS PREPARATION CONTAINING ESTRADIOL
(FR) PREPARATION A ADMINISTRATION PERCUTANEE, CONTENANT DE L'×STRADIOL
Abstract:
(EN) A percutaneous preparation containing estradiol as the pharmaceutically active ingredient and the following components as the base: (1) an elastic polymer of the formula (A-B)nX or (A-B)n-A, wherein A represents substantially a block of a monovinyl-substituted aromatic compound polymer, B represents substantially a block of a conjugated diolefin copolymer, n is an integer of 3 to 7, and X represents a residue of a polyfunctional compound to which are bonded n polymer (A-B) chains, (2) crotamiton, and (3) a water-absorbent polymer. It has a sufficient drug efficacy and does not cause redness or eruption.
(FR) Une préparation pour administration percutanée contient de l'÷stradiol comme ingrédient actif et les composants de base suivants: (1) un polymère élastique de la formule (A-B)nX ou (A-B)n-A, dans laquelle A représente essentiellement un bloc de composé polymère aromatique à substitution de monovinyle, B représente essentiellement un bloc de copolymère de dioléfine, n est un nombre entier de 3 à 7, et X représente un reste d'un composé polyfonctionnel auquel sont liés n chaînes (A-B) de polymère, (2) du crotamiton et (3) un polymère absorbant l'eau. Ladite préparation a une efficacité thérapeutique suffisante et n'entraîne aucune rougeur ou éruption.
Designated States: AU, CA, JP, KR, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
EP0483370US5248676CA2066249AU1991077800