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1. (WO1991017187) A 35kD TUMOR ASSOCIATED PROTEIN ANTIGEN: USES AND METHODS OF DETECTION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/017187 International Application No.: PCT/US1991/002638
Publication Date: 14.11.1991 International Filing Date: 17.04.1991
Chapter 2 Demand Filed: 02.11.1991
IPC:
C07K 14/47 (2006.01) ,C07K 16/30 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
30
from tumour cells
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 300 Lakeside Drive 22nd Floor Oakland, CA 94612-3550, US
Inventors:
WONG, Jan, H.; US
GUPTA, Rishab, K.; US
MORTON, Donald, L.; US
Agent:
CAMPBELL, Cathryn ; Pretty, Schroeder, Brueggemann & Clark 444 South Flower Street Suite 2000 Los Angeles, CA 90071, US
UEXKÜLL & STOLBERG; Beselerstr. 4 D-2000 Hamburg 52, DE
Priority Data:
510,60218.04.1990US
Title (EN) A 35kD TUMOR ASSOCIATED PROTEIN ANTIGEN: USES AND METHODS OF DETECTION
(FR) ANTIGENE PROTEIQUE ASSOCIE A UNE TUMEUR DE 35 kD: EMPLOIS ET PROCEDES DE DETECTION
Abstract:
(EN) This invention provides the isolation and characterization of a tumor associated antigen which can be used for immunodiagnosis, immunoprognosis, and therapy of human cancer. The antigen is a protein molecule with a molecular weight of about 35 kD after reduction and separation by SDS-polyacrylamide gel electrophoresis. The antigen has been detected in serum of cancer patients.
(FR) Isolation et caractérisation d'un antigène associé à une tumeur, lequel peut être utilisé dans l'immunodiagnostic, l'immunopronostic, et la thérapie du cancer chez l'homme. L'antigène est une molécule protéique d'une masse moléculaire d'environ 35 kD après réduction et séparation par électrophorèse sur gel de SDS-polyacrylamine. On a détecté l'antigène dans du sérum prélevé sur des patients atteints d'un cancer.
Designated States: AT, BB, BG, BR, CA, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, PL, RO, SD, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0529007JPH05506241CA2080835