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1. (WO1991017178) METHOD FOR PURIFYING RECOMBINANTLY-PRODUCED PROTEINS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/017178 International Application No.: PCT/US1991/003152
Publication Date: 14.11.1991 International Filing Date: 07.05.1991
Chapter 2 Demand Filed: 05.12.1991
IPC:
C07K 14/755 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
745
Blood coagulation or fibrinolysis factors
755
Factors VIII
Applicants:
RORER INTERNATIONAL (HOLDINGS), INC. [US/US]; 40 Cape Henlopen Drive Wilmington, DE 19958, US (AllExceptUS)
DARLING, Thomas, L., J. [US/US]; US (UsOnly)
AKHNANA, Lida, Y. [US/US]; US (UsOnly)
MITSCHELEN, Jonathan, J. [US/US]; US (UsOnly)
HRINDA, Michael, E. [US/US]; US (UsOnly)
Inventors:
DARLING, Thomas, L., J.; US
AKHNANA, Lida, Y.; US
MITSCHELEN, Jonathan, J.; US
HRINDA, Michael, E.; US
Agent:
GOODMAN, Rosanne; Rhone-Poulenc Rorer Inc. 500 Arcola Drive P.O. Box 1200 Collegeville, PA 19426-0107, US
Priority Data:
519,70907.05.1990US
Title (EN) METHOD FOR PURIFYING RECOMBINANTLY-PRODUCED PROTEINS
(FR) PROCEDE PERMETTANT DE PURIFIER DES PROTEINES PRODUITES PAR RECOMBINAISON
Abstract:
(EN) This invention provides a method for the recovery of recombinantly produced proteins using mechanical disruption of the inclusion bodies in the method. Specifically, the invention provides a method for recovering vWF fragment from inclusion bodies of transformed $i(E. coli).
(FR) Cette invention concerne un procédé de récupération de protéines produites par recombinaison, qui utilise la rupture mécanique des corps d'inclusion dudit procédé. Plus spécifiquement, l'invention concerne un procédé de récupération de fragment vWF provenant de corps d'inclusion du gène $i(E. coli) transformé.
Designated States: AU, CA, JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1991079553