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1. (WO1991017176) NOVEL STEROID GLYCOSIDES USEFUL IN THE EARLY DETECTION OF HYPERTENSION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/017176 International Application No.: PCT/US1991/003050
Publication Date: 14.11.1991 International Filing Date: 03.05.1991
Chapter 2 Demand Filed: 06.12.1991
IPC:
C07J 17/00 (2006.01) ,C07J 19/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
J
STEROIDS
17
Normal steroids containing carbon, hydrogen, halogen, or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta[a]hydrophenanthrene skeleton
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
J
STEROIDS
19
Normal steroids containing carbon, hydrogen, halogen, or oxygen, substituted in position 17 by a lactone ring
Applicants:
THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON [US/US]; 3755 University Way N.E. Seattle, WA 98195, US
Inventors:
KENNY, Margaret, A.; US
AHMAD, Suhail; US
MALIK, Sohail; US
Agent:
SHARKEY, Richard, G. ; Seed and Berry 6300 Columbia Center Seattle, WA 98104-7092, US
BROWN, John, D.; Forrester & Boehmert Widenmayerstrasse 4 D-8000 München 22, DE
Priority Data:
520,17507.05.1990US
Title (EN) NOVEL STEROID GLYCOSIDES USEFUL IN THE EARLY DETECTION OF HYPERTENSION
(FR) NOUVEAUX GLYCOSIDES STEROIDES UTILES POUR LA DETECTION PRECOCE DE L'HYPERTENSION
Abstract:
(EN) The present invention discloses compounds useful for the screening or monitoring of hypertensive individuals, for correction of interference in the measurement of digoxin levels in patients, and as pressor agents, potassium sparing diuretics, natriuretics, or agents that alter cellular calcium levels. Methods for detecting the presence or amount of the compounds are also provided.
(FR) La présente invention se rapporte à des composés utiles au dépistage et à la surveillance de l'hypertension chez des individus, à la correction d'une interférence dans l'évaluation de niveaux de digoxine chez des patients, et comme agents vasoconstricteurs, comme diurétiques entraînant une perte réduite de potassium, comme natriurétiques ou comme agents servant à modifier les niveaux de calcium cellulaire. Des procédés pour détecter la présence ou le niveau de ces composés sont aussi décrits.
Designated States: AU, CA, HU, JP, KR
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL98065EP0530224AU1991077943