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1. (WO1991017156) NEUROPROTECTIVE INDOLONE AND RELATED DERIVATIVES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/017156 International Application No.: PCT/US1991/001470
Publication Date: 14.11.1991 International Filing Date: 04.03.1991
Chapter 2 Demand Filed: 23.08.1991
IPC:
C07D 401/06 (2006.01) ,C07D 413/06 (2006.01) ,C07D 451/04 (2006.01) ,C07D 451/06 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
451
Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
02
containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane; Cyclic acetals thereof
04
with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring system
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
451
Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
02
containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane; Cyclic acetals thereof
04
with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring system
06
Oxygen atoms
Applicants:
PFIZER INC [US/US]; 235 East 42nd Street New York, NY 10017, US (AllExceptUS)
CHENARD, Bertrand, Leo [US/US]; US (UsOnly)
Inventors:
CHENARD, Bertrand, Leo; US
Agent:
LUMB, J., Trevor ; Pfizer Inc. Eastern Point Road Groton, CT 06340, US
Priority Data:
522,33210.05.1990US
Title (EN) NEUROPROTECTIVE INDOLONE AND RELATED DERIVATIVES
(FR) INDOLONE NEUROPROTECTEUR ET DERIVES APPARENTES
Abstract:
(EN) 5-(1-Hydroxy-2-piperidinopropyl)-2(1H,3H)-indolone derivatives and analogs; pharmaceutical compositions thereof; methods of treating CNS disorders therewith; and intermediates useful in the preparation of said compounds.
(FR) Dérivés de 5-(1-hydroxy-2-piperidinopropyle)-2(1H,3H)-indolone et analogues; compositions pharmaceutiques les contenant; procédés servant à traiter des troubles du système nerveux central avec ces compositions; et intermédiaires utiles dans la préparation des composés de la présente invention.
Designated States: AU, BR, CA, FI, HU, JP, KR, NO, PL, RO, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI925069FI982654NO19924310IL98056EP0554247US5306723
JPH05506433CA2080475KR1019930700482AU1991074565