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1. (WO1991016929) A PHARMACEUTICAL PREPARATION CONTAINING N-GLYCOFUROLS AND N-ETHYLENE GLYCOLS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/016929 International Application No.: PCT/DK1991/000119
Publication Date: 14.11.1991 International Filing Date: 03.05.1991
Chapter 2 Demand Filed: 07.10.1991
IPC:
A61K 9/00 (2006.01) ,A61K 38/26 (2006.01) ,A61K 38/28 (2006.01) ,A61K 47/10 (2006.01) ,A61K 47/22 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
26
Glucagons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
28
Insulins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
22
Heterocyclic compounds
Applicants:
NOVO NORDISK A/S [DK/DK]; Novo Allé DK-2880 Bagsværd, DK
Inventors:
BECHGAARD, Erik; DK
GIZURARSON, Sveinbjörn; IS
HJORTKJÆR, Rolf, Kühlman; DK
Agent:
NOVO NORDISK A/S; Patent Department Novo Allé DK-2880 Bagsvaerd, DK
Priority Data:
1170/9010.05.1990DK
2075/9030.08.1990DK
Title (EN) A PHARMACEUTICAL PREPARATION CONTAINING N-GLYCOFUROLS AND N-ETHYLENE GLYCOLS
(FR) PREPARATION PHARMACEUTIQUE CONTENANT DES n-GLYCOFUROLS ET DES n-ETHYLENE GLYCOLS
Abstract:
(EN) A pharmaceutical preparation for application of biologically active substance(s) to a mucosal membrane of a mammal comprising one or more substance(s) selected from the group consisting of n-glycofurols represented by formula (I), wherein n is 1 to 8, and n-ethylene glycols represented by the formula (II): H(OCH2CH2)pOH, wherein p is 1 to 14, produces a high plasma concentration of the pharmaceutically active substance(s) nearly as rapid as by i.v. administration.
(FR) La préparation pharmaceutique décrite, qui permet l'application de substance(s) biologiquement active(s) sur une membrane des muqueuses d'un mammifère, comprend une ou plusieurs substance(s) choisie(s) dans le groupe composé des n-glycofurols représentés par la formule (I), où n est compris entre 1 et 8, et des n-éthylènes glycols représentés par la formule (II): H(OCH2CH2)pOH, où p est compris entre 1 et 14. Une telle préparation produit dans le plasma une concentration élevée de la substance ou des substances pharmaceutiquement active(s) presque aussi rapidement que par administration intraveineuse.
Designated States: AU, BG, BR, CA, FI, HU, JP, KP, KR, NO, PL, RO, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0532546CA2082495AU1991078809DK0532546