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1. (WO1991016915) MATURATION OF HEMOPOIETIC CELLS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/016915 International Application No.: PCT/EP1991/000821
Publication Date: 14.11.1991 International Filing Date: 30.04.1991
IPC:
A61K 38/17 (2006.01) ,A61K 38/20 (2006.01) ,C07K 14/735 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
20
Interleukins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
735
Fc receptors
Applicants:
CIBA-GEIGY AG [CH/CH]; Klybeckstrasse 141 CH-4002 Basle, CH (AllExceptUS)
DEBRE, Patrice [FR/FR]; FR (UsOnly)
MOSSALAYI, Mohammad, Djavad [IR/FR]; FR (UsOnly)
Inventors:
DEBRE, Patrice; FR
MOSSALAYI, Mohammad, Djavad; FR
Common
Representative:
CIBA-GEIGY AG; Patentabteilung Klybeckstrasse 141 CH-4002 Basle, CH
Priority Data:
9010356.509.05.1990GB
Title (EN) MATURATION OF HEMOPOIETIC CELLS
(FR) MATURATION DE CELLULES HEMOPOIETIQUES
Abstract:
(EN) The invention concerns the use of IgE-binding factor (IgE-bf) for the stimulation of the maturation, i.e. of the differentiation and proliferation, of myeloid precursor cells in context with interleukin-1 (IL-1). The invention further concerns a pharmaceutical preparation comprising IgE-bf either alone or in combination with IL-1 for the treatment or prevention of diseases by stimulating the maturation of myeloid precursor cells.
(FR) L'invention concerne l'utilisation du facteur de liaison de l'IgE (IgE-bf) servant à la stimulation de la maturation, c'est-à-dire de la différenciation et de la prolifération, de cellules précurseurs myéloïdes dans un contexte dans lequel est présente l'interleukine-1(IL-1). L'invention se rapporte, de plus, à une préparation pharmaceutique comprenant IgE-bf seul ou en combinaison avec IL-1, ayant pour but de traiter ou de prévenir des maladies en stimulant la maturation de cellules précurseurs myéloïdes.
Designated States: AU, CA, JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0484477US5246699CA2056359PT97591AU1991077647