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1. (WO1991016896) PHARMACEUTICAL COMPOSITION FOR USE IN TREATING PAIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/016896 International Application No.: PCT/US1991/002985
Publication Date: 14.11.1991 International Filing Date: 01.05.1991
Chapter 2 Demand Filed: 29.11.1991
IPC:
A61K 31/557 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
557
Eicosanoids, e.g. leukotrienes
Applicants:
G.D. SEARLE & CO. [US/US]; P.O. Box 5110 Chicago, IL 60680-5110, US (AllExceptUS)
RAFFERTY, Michael, F. [US/US]; US (UsOnly)
STAPELFELD, Awilda [US/US]; US (UsOnly)
Inventors:
RAFFERTY, Michael, F.; US
STAPELFELD, Awilda; US
Agent:
WILLIAMS, Roger, A. ; G.D. Searle & Co. P.O. Box 5110 Chicago, IL 60680-5110, US
WOLFF, Hans, Joachim ; Adelonstrasse 58 Postfach 80 01 40 D-6230 Frankfurt am Main 80, DE
Priority Data:
518,36803.05.1990US
Title (EN) PHARMACEUTICAL COMPOSITION FOR USE IN TREATING PAIN
(FR) COMPOSITION PHARMACEUTIQUE UTILISEE DANS LE TRAITEMENT DE DOULEURS
Abstract:
(EN) A pharmaceutical composition and a method for treating mild to moderate pain in a subject in need of such treatment is performed by administering an analgesic agent selected from diclofenac, ibuprofen, piroxicam and their pharmaceutically acceptable salts in a dosage which by itself would provide less than the therapeutic effect, and administering misoprostol in a dosage which is sufficient to potentiate the analgesic effect of the analgesic agent to the therapeutic effect.
(FR) Composition pharmaceutique et procédé de traitement de douleurs bénignes à modérées chez un sujet nécessitant un tel traitement, consistant à administrer un agent analgésique choisi parmi le diclofénac, l'ibuprofène, le piroxycam ainsi que leurs sels pharmaceutiquement acceptables en une posologie qui par elle-même a un effet inférieur à l'effet thérapeutique, et à administrer du misoprostol en une posologie suffisante pour potentialiser l'effet analgésique de l'agent analgésique jusqu'à obtention de l'effet thérapeutique.
Designated States: AT, AU, BB, BG, BR, CA, CH, DE, DK, ES, FI, GB, HU, JP, KP, KR, LK, LU, MC, MG, MW, NL, NO, PL, RO, SD, SE, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1991077937