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1. (WO1991016891) TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) BY INHALATION OF AN IMIDAZOLINE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/016891 International Application No.: PCT/US1991/002916
Publication Date: 14.11.1991 International Filing Date: 03.05.1991
Chapter 2 Demand Filed: 05.12.1991
IPC:
A61K 31/415 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
415
1,2-Diazoles
Applicants:
AEGIS TECHNOLOGY, INC. [US/US]; 70 Phillips Street Wickford, RI 02852, US
Inventors:
SKUPIN, Alvaro, H.; US
Agent:
PATTERSON, Herbert, W. ; Finnegan, Henderson, Farabow, Garrett & Dunner 1300 I Street, N.W. Washington, DC 20005-3315, US
TURNER, John, B.; Finnegan, Henderson, Farabow, Garrett & Dunner 1300 I Street, N.W. Washington, DC 20005-3315, US
Priority Data:
518,71607.05.1990US
Title (EN) TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) BY INHALATION OF AN IMIDAZOLINE
(FR) PROCEDE DE TRAITEMENT DE LA BRONCHOPNEUMOPATHIE CHRONIQUE OBSTRUCTIVE (COPD) PAR L'INHALATION D'UNE IMIDAZOLINE
Abstract:
(EN) A method of using an imidazoline compound, which is a vasodilator and an alpha-adrenergic blocking agent, for the treatment of symptoms of chronic obstructive pulmonary diseases (COPD), including cystic fibrosis, chronic bronchitis and emphysema, or COPD where it is associated with asthma, comprises administering the imidazoline to a patient by inhalation. Preferably the imidazoline compound employed is tolazoline. The presentation of an imidazoline compound in a device for the administration of an aerosol is disclosed.
(FR) Procédé d'utilisation d'un composé d'imidazoline, qui est un vasodilatateur et un alpha-adrénolytique, pour le traitement des symptômes des bronchopneumopathies chroniques obstructives (COPD) telles que la fibrose kystique, la bronchite chronique et l'emphysème, ou des COPD lorsqu'elles sont associées à l'asthme, ledit procédé consistant à administrer le composé d'imidazoline au malade par inhalation. De préférence, le composé d'imidazoline utilisé est la tolazoline. On a prévu la présentation d'un composé d'imidazoline dans un dispositif servant à l'administration d'un aérosol.
Designated States: AT, AU, BB, BG, BR, CA, CH, DE, DK, ES, FI, GB, HU, JP, KP, KR, LK, LU, MC, MG, MW, NL, NO, PL, RO, SD, SE, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI925002NO19924297EP0527925US5250286JPH05507083CA2081768
AU1991078988