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1. (WO1991009055) ACYLATED BRADYKININ ANTAGONISTS AND USES THEREFOR
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/009055 International Application No.: PCT/US1990/007268
Publication Date: 27.06.1991 International Filing Date: 10.12.1990
Chapter 2 Demand Filed: 03.07.1991
IPC:
A61K 38/00 (2006.01) ,C07K 7/18 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
18
Kallidins; Bradykinins; Related peptides
Applicants:
BOSTON UNIVERSITY [US/US]; 881 Commonwealth Avenue Boston, MA 02115, US
Inventors:
GAVRAS, Haralambos; US
LAMMEK, Bernard; PL
Agent:
GRANAHAN, Patricia ; Hamilton, Brook, Smith & Reynolds Two Militia Drive Lexington, MA 02173, US
Priority Data:
447,71308.12.1989US
Title (EN) ACYLATED BRADYKININ ANTAGONISTS AND USES THEREFOR
(FR) ANTAGONISTES ACYLES DE BRADYKININE ET LEURS UTILISATIONS
Abstract:
(EN) A class of acylated bradykinin analogs which are potent bradykinin antagonists is disclosed. The acylated bradykinin analogs exhibit greatly improved bradykinin antagonistic potency, and can be used for the diagnosis and/or treatment of bradykinin-mediated disorders.
(FR) On décrit une catégorie d'analogues acylés de bradykinine qui constituent de puissants antagonistes contre la bradykinine. Lesdits analogues possèdent une puissance antagoniste contre la bradykinine grandement accrue, et peuvent être utilisés pour le diagnostic et/ou le traitement de troubles dus à la bradykinine.
Designated States: JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0502987