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1. (WO1991009031) TRIFLUOROMETHYL SUBSTITUTED COMPOUNDS AND A PHARMACEUTICAL COMPOSITION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/009031 International Application No.: PCT/GB1990/001935
Publication Date: 27.06.1991 International Filing Date: 11.12.1990
IPC:
C07D 311/22 (2006.01) ,C07D 311/58 (2006.01) ,C07D 311/68 (2006.01) ,C07D 405/04 (2006.01) ,C07D 493/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
311
Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02
ortho- or peri-condensed with carbocyclic rings or ring systems
04
Benzo [b] pyrans, not hydrogenated in the carbocyclic ring
22
with oxygen or sulfur atoms directly attached in position 4
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
311
Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02
ortho- or peri-condensed with carbocyclic rings or ring systems
04
Benzo [b] pyrans, not hydrogenated in the carbocyclic ring
58
other than with oxygen or sulfur atoms in position 2 or 4
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
311
Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02
ortho- or peri-condensed with carbocyclic rings or ring systems
04
Benzo [b] pyrans, not hydrogenated in the carbocyclic ring
58
other than with oxygen or sulfur atoms in position 2 or 4
68
with nitrogen atoms directly attached in position 4
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
04
directly linked by a ring-member-to-ring- member bond
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
493
Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
BEECHAM GROUP PLC [GB/GB]; SB House Great West Road Brentford Middlesex TW8 9BD, GB (AllExceptUS)
EVANS, John, Morris [GB/GB]; GB (UsOnly)
STEMP, Geoffrey [GB/GB]; GB (UsOnly)
TEDDER, John, Martin [GB/GB]; GB (UsOnly)
Inventors:
EVANS, John, Morris; GB
STEMP, Geoffrey; GB
TEDDER, John, Martin; GB
Agent:
RUTTER, Keith; SmithKline Beecham Corporate Patents Great Burgh, Yew Tree Bottom Road Epsom Surrey KT18 5XQ, GB
Priority Data:
8927978.011.12.1989GB
8927979.811.12.1989GB
9005492.512.03.1990GB
Title (EN) TRIFLUOROMETHYL SUBSTITUTED COMPOUNDS AND A PHARMACEUTICAL COMPOSITION
(FR) COMPOSES A SUBSTITUTION TRIFLUOROMETHYLE ET COMPOSITION PHARMACEUTIQUE
Abstract:
(EN) A compound of formula (I) or, where appropriate, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, wherein A1, A2, A3, A4, R1, R2, R3, R4 and Y are as defined herein; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compound and composition in medicine.
(FR) Composé ayant la formule (I) ou, dans les cas appropriés, un de ses sels ou un de ses solvates pharmaceutiquement acceptables. Dans la formule (I), A1, A2, A3, A4, R1, R2, R3, R4 et Y ont la définition décrite. Procédé de préparation de ce composé, composition pharmaceutique contenant ce composé, utilisation de ce composé et de cette composition en médecine.
Designated States: JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)