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1. (WO1991009023) N-HETEROARALKYL-SUBSTITUTED 1-ARYLOXY-2-PROPANOLAMINE AND PROPYLAMINE DERIVATIVES POSSESSING CLASS III ANTIARRHYTHMIC ACTIVITY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/009023 International Application No.: PCT/US1990/007061
Publication Date: 27.06.1991 International Filing Date: 03.12.1990
IPC:
C07D 215/12 (2006.01) ,C07D 235/14 (2006.01) ,C07D 241/42 (2006.01) ,C07D 263/56 (2006.01) ,C07D 307/81 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
215
Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
02
having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
12
with substituted hydrocarbon radicals attached to ring carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
235
Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02
condensed with carbocyclic rings or ring systems
04
Benzimidazoles; Hydrogenated benzimidazoles
06
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
14
Radicals substituted by nitrogen atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
241
Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
36
condensed with carbocyclic rings or ring systems
38
with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
40
Benzopyrazines
42
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
263
Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
52
condensed with carbocyclic rings or ring systems
54
Benzoxazoles; Hydrogenated benzoxazoles
56
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
307
Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77
ortho- or peri-condensed with carbocyclic rings or ring systems
78
Benzo [b] furans; Hydrogenated benzo [b] furans
79
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
81
Radicals substituted by nitrogen atoms not forming part of a nitro radical
Applicants:
AMERICAN HOME PRODUCTS CORPORATION [US/US]; 685 Third Avenue New York, NY 10017, US
Inventors:
BUTERA, John, Anthony; US
BAGLI, Jehan, Framoz; US
Agent:
ALICE, Ronald, W.; American Home Products Corporation 685 Third Avenue New York, NY 10017 , US
Priority Data:
451,39111.12.1989US
521,78710.05.1990US
Title (EN) N-HETEROARALKYL-SUBSTITUTED 1-ARYLOXY-2-PROPANOLAMINE AND PROPYLAMINE DERIVATIVES POSSESSING CLASS III ANTIARRHYTHMIC ACTIVITY
(FR) 1-ARYLOXY-2-PROPANOLAMINE A SUBSTITUTION N-HETEROARALKYLE ET DERIVES DE PROPYLAMINE POSSEDANT UNE ACTIVITE ANTIARRHYTHMIQUE DE CLASSE III
Abstract:
(EN) This invention relates to N-heteroalkyl-substituted 1-aryloxy-2-propanolamine and propylamine derivatives possessing anti-arrhythmic activity, to pharmaceutical compositions and to methods for production thereof.
(FR) 1-aryloxy-2-propanolamine à substitution N-hétéroalkyle et dérivés de propalamine possédant une activité antiarrhythmique, compositions pharmaceutiques et leurs procédés de production.
Designated States: AU, CA, JP, KR
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1991069773