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1. (WO1991008769) PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING RETROVIRAL INFECTIONS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/008769 International Application No.: PCT/FR1990/000921
Publication Date: 27.06.1991 International Filing Date: 18.12.1990
Chapter 2 Demand Filed: 15.07.1991
IPC:
A61K 31/16 (2006.01) ,A61K 31/19 (2006.01) ,A61K 38/04 (2006.01) ,A61K 38/55 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55
Protease inhibitors
Applicants:
TRANSGENE S.A. [FR/FR]; 11, rue de Molsheim F-67082 Strasbourg Cédex, FR (AllExceptUS)
GUY, Bruno [FR/FR]; FR (UsOnly)
LECOCQ, Jean-Pierre [BE/FR]; FR (UsOnly)
Inventors:
GUY, Bruno; FR
LECOCQ, Jean-Pierre; FR
Agent:
WARCOIN, Jacques; Cabinet Regimbeau 26, avenue Kléber F-75116 Paris, FR
MARTIN, Jean-Jacques; Cabinet Regimbeau 26, avenue Kléber F-75116 Paris, FR
Priority Data:
89/1672618.12.1989FR
90/1310223.10.1990FR
Title (EN) PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING RETROVIRAL INFECTIONS
(FR) COMPOSITION PHARMACEUTIQUE DESTINEE AU TRAITEMENT OU A LA PREVENTION DES INFECTIONS RETROVIRALES
Abstract:
(EN) A pharmaceutical composition for treating or preventing retroviral diseases containing a thiol-protease inhibitor as an active principle. Thiol-protease inhibitors are known products such as cystatines and the derivatives thereof, antipaine [(S)-1-carboxy-2-phenyletyl]-carbamoyl-Arg-Val-Arg-al, E-64 (L-trans-epoxysuccinyl-leucylamide-(4-guanidino)-butane, N-[N-(L-3-transcarboxyirane-2-carbonyl)-L-leucyl]-agmatine, leupeptin, iodoacetic acid/iodoacetamide or N-Cbz-Phe-Ala-diazomethane.
(FR) L'invention se rapporte à une composition pharmaceutique pour le traitement ou la prévention des maladies à rétrovirus comprenant, à titre de principe actif, un inhibiteur de thiol-protéases. Les inhibiteurs de thiol-protéases sont des produits connus; par exemple les cystatines et leurs dérivés, l'antipaïne [(S)-1-carboxy-2-phenylethyl]-carbamoyl-Arg-Val-Arg-al, E-64 (L-trans-epoxysuccinyl-leucylamide-(4-guanidino)-butane, N-[N-(L-3-transcarboxyirane-2-carbonyl)-L-leucyl]-agmatine, la leupeptine, l'acide iodoacétique/iodoacétamide ou le N-Cbz-Phe-Ala-diazométhane.
Designated States: AU, CA, JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
EP0506769JPH05502868CA2071972AU1991069755