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1. (WO1991008475) METHOD AND DEVICE FOR THE RAPID ELECTROANALYSIS OF BIOLOGICAL LIQUIDS AND APPLICATIONS IN THE BIOLOGICAL FIELD
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/008475 International Application No.: PCT/FR1990/000866
Publication Date: 13.06.1991 International Filing Date: 30.11.1990
IPC:
G01N 27/48 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
416
Systems
48
using polarography, i.e. measuring changes in current under a slowly-varying voltage
Applicants:
PARACELSE S.A.R.L. [FR/FR]; 21, rue de Fécamp F-75012 Paris, FR (AllExceptUS)
BUVET, René [FR/FR]; FR (UsOnly)
MOUTET, Marc [FR/FR]; FR (UsOnly)
BANISSI, Claire [FR/FR]; FR (UsOnly)
Inventors:
BUVET, René; FR
MOUTET, Marc; FR
BANISSI, Claire; FR
Agent:
CABINET GEFIB; 59, rue Edouard-Vaillant F-92300 Levallois-Perret, FR
Priority Data:
89/1590401.12.1989FR
Title (EN) METHOD AND DEVICE FOR THE RAPID ELECTROANALYSIS OF BIOLOGICAL LIQUIDS AND APPLICATIONS IN THE BIOLOGICAL FIELD
(FR) PROCEDE D'ELECTRO ANALYSE RAPIDE DES LIQUIDES BIOLOGIQUES, DISPOSITIF UTILISE A CET EFFET ET APPLICATIONS DANS LE DOMAINE BIOLOGIQUE
Abstract:
(EN) The invention relates to the field of chemistry and more particularly of biological chemistry. The object of the invention is a rapid electroanalysis method for analysing biological liquids by cyclic voltametry with linear potential scanning on porous graphite electrode, the method consisting in subjecting the sample to be analysed, present in the graphite capillarity, without previous separation, after a first scanning of potentials, to a second scanning and optionally a third scanning back and forth and in recording the newly appeared peaks. The invention also relates to the voltametry device with graphite electrode used for implementing the electroanalysis method of the invention. Application of the method of the invention to the detection and/or metering in biological liquids of catabolites of neuromediators, of metabolism substances, of toxic or illicit substances.
(FR) L'invention se rapporte au domaine de la chimie et plus particulièrement à celui de la chimie biologique. Elle a en particulier pour objet, un procédé d'électro-analyse rapide des liquides biologiques par voltamétrie cyclique à balayage linéaire de potentiel sur électrode poreuse de graphite qui consiste en ce que l'on soumet l'échantillon à analyser, présent dans la capillarité du graphite, sans séparation préalable, après un premier balayage de potentiels, à un second balayage et éventuellement à un troisième balayage aller et retour et en ce qu'on enregistre les pics nouveaux apparus. L'invention concerne aussi le dispositif de voltamétrie à électrode de graphite utilisé pour la mise en ÷uvre du procédé d'électro-analyse de l'invention. Application du procédé selon l'invention à la détection et/ou le dosage dans les liquides biologiques de catabolites de neuromédiateurs, de substances du métabolisme, de substances toxiques ou illicites.
Designated States: AU, BR, CA, FI, HU, JP, KR, NO, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
EP0465611AU1991069607FR2656424