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1. (WO1991008294) NOVEL VACCINE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/008294 International Application No.: PCT/EP1990/002034
Publication Date: 13.06.1991 International Filing Date: 26.11.1990
Chapter 2 Demand Filed: 04.06.1991
IPC:
A61K 39/00 (2006.01) ,C07K 14/235 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
235
from Bordetella (G)
Applicants:
SMITHKLINE BEECHAM BIOLOGICALS (S.A.) [BE/BE]; 89, rue de l'Institut B-1332 Genval, BE (AllExceptUS)
LOCHT, Camille [BE/FR]; FR (UsOnly)
LOBET, Yves [BE/BE]; BE (UsOnly)
Inventors:
LOCHT, Camille; FR
LOBET, Yves; BE
Agent:
TYRRELL, Arthur, William, Russell ; SmithKline Beecham Corporate Patents, Great Burgh Yew Tree Bottom Road Epsom Surrey KT18 5XQ, GB
Priority Data:
442,80829.11.1989US
455,64822.12.1989US
Title (EN) NOVEL VACCINE
(FR) NOUVEAU VACCIN
Abstract:
(EN) The $i(Bordetella pertussis) toxin is genetically modified to express a toxin protein which is deficient in target-cell receptor binding and is used in a vaccine for protection against whooping cough.
(FR) On modifie génétiquement la toxine $i(Bordetella pertussis) afin d'exprimer une protéine de toxine présentant une insuffisance dans la liaison du récepteur des cellules cibles, et on l'utilise dans un vaccin contre la coqueluche.
Designated States: AU, CA, JP, KR, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0502016US6040427CA2069622KR1019920703098AU1990067363