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1. (WO1991008289) SPERM SPECIFIC NUCLEAR AUTOANTIGENIC PROTEIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/008289 International Application No.: PCT/US1990/006869
Publication Date: 13.06.1991 International Filing Date: 23.11.1990
Chapter 2 Demand Filed: 24.06.1991
IPC:
C07K 14/47 (2006.01) ,G01N 33/564 (2006.01) ,G01N 33/68 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
564
for pre-existing immune complex or autoimmune disease
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL [US/US]; Office of Research Services 300 Bynum Hall Campus Box 4100 Chapel Hill, NC 27599-4100, US
Inventors:
O'RAND, Michael, G.; US
ZIMMERMAN, Lisa, J.; US
WELCH, Jeffrey, E.; US
Agent:
SIBLEY, Kenneth, D. ; Bell, Seltzer, Park & Gibson P.O. Drawer 34009 Charlotte, NC 28234, US
Priority Data:
441,09524.11.1989US
Title (EN) SPERM SPECIFIC NUCLEAR AUTOANTIGENIC PROTEIN
(FR) PROTEINE NUCLEAIRE AUTOANTIGENIQUE SPECIFIQUE DE SPERME
Abstract:
(EN) Disclosed is a DNA sequence which codes for Sperm Nuclear Autoantigenic Protein (SNAP) or a fragment thereof. Essentially pure SNAP is also disclosed. The DNA sequence which codes for human SNAP and the DNA sequence which codes for rabbit SNAP are specifically disclosed. SNAP is useful as an immunocontraceptive agent and in the diagnosis of autoimmune infertility.
(FR) Est décrite une séquence d'ADN codant pour une protéine nucléaire autoantigénique de sperme (PNAS) ou un fragment de celle-ci. Est également décrite une PNAS pure. La séquence d'ADN codant pour la PNAS humaine et la séquence d'ADN codant pour la PNAS du lapin sont décrites. La PNAS est utile en tant qu'agent immunocontraceptif et dans le diagnostic de l'infécondité d'origine immunitaire.
Designated States: AU, CA, FI, JP, KR, NO
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)