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1. (WO1991008285) PRODUCTION OF RECOMBINANT HUMAN INTERLEUKIN-1 INHIBITOR
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/008285 International Application No.: PCT/US1990/006979
Publication Date: 13.06.1991 International Filing Date: 29.11.1990
Chapter 2 Demand Filed: 27.06.1991
IPC:
C07K 14/54 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
52
Cytokines; Lymphokines; Interferons
54
Interleukins (IL)
Applicants:
SYNERGEN, INC. [US/US]; 1885 33rd Street Boulder, CO 80301, US
Inventors:
HAGEMAN, Robert; US
EISENBERG, Stephen, P.; US
DRIPPS, David; US
EVANS, Ronald; US
CUDNY, Henryk; US
THOMPSON, Robert, C.; US
Agent:
PATTERSON, Herbert, W. ; Finnegan, Henderson, Farabow, Garrett & Dunner 1300 I Street, N.W. Washington, DC 20005-3315, US
MULLEN, Clair, X.; Finnegan, Henderson, Farabow, Garrett & Dunner 1300 I Street, N.W. Washington, DC 20005-3315, US
Priority Data:
442,65229.11.1989US
Title (EN) PRODUCTION OF RECOMBINANT HUMAN INTERLEUKIN-1 INHIBITOR
(FR) PRODUCTION D'INHIBITEUR D'INTERLEUKINE-1 HUMAINE RECOMBINEE
Abstract:
(EN) A method for the production of commercial quantities of highly purified interleukin-1 inhibitor (IL-li) from a recombinant host is disclosed. A preferred recombinant $i(E. coli) host for sue in this method is also disclosed.
(FR) Procédé de production de quantités commerciales d'inhibiteur d'interleukine-1 hautement purifiée (IL-1i) à partir d'un hôte recombiné. Un hôte de $i(E. coli) recombiné préféré utilisé dans ce procédé est également décrit.
Designated States: AT, AU, BB, BG, BR, CA, CH, DE, DK, ES, FI, GB, HU, JP, KP, KR, LK, LU, MC, MG, MW, NL, NO, RO, SD, SE, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI922434NO19922138EP0502956CA2068320KR1019920703792AU1991069007