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1. (WO1991007986) METHOD OF TREATING SEPTIC SHOCK
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/007986 International Application No.: PCT/US1990/006872
Publication Date: 13.06.1991 International Filing Date: 30.11.1990
Chapter 2 Demand Filed: 28.06.1991
IPC:
A61K 38/00 (2006.01) ,C07K 16/24 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
24
against cytokines, lymphokines or interferons
Applicants:
SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road Kenilworth, NJ 07033, US (AllExceptUS)
STARNES, H., Fletcher [US/US]; US
ABRAMS, John, S. [US/US]; US (UsOnly)
Inventors:
STARNES, H., Fletcher; US
ABRAMS, John, S.; US
Agent:
BLASDALE, John, H., C. ; Schering-Plough Corporation One Giralda Farms Madison, NJ 07940-1000, US
Priority Data:
445,19204.12.1989US
Title (EN) METHOD OF TREATING SEPTIC SHOCK
(FR) METHODE DE TRAITEMENT DE CHOC SEPTIQUE
Abstract:
(EN) A method of treating septic shock is provided. The method comprises administering an effective amount of an antagonist to human IL-6. Preferably, the antagonist is a blocking monoclonal antibody specific for human IL-6, or a fragment or binding composition derived therefrom.
(FR) La méthode de traitement de choc septique consiste à administrer une quantité efficace d'un antagoniste au IL-6 humain. De préférence, l'antagoniste est un corps monoclonal de blocage spécifique au IL-6 humain, ou un fragment ou une composition de liaison dérivé de cet anticorps.
Designated States: AU, BB, BG, BR, CA, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, RO, SD, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI922551EP0504307JPH05504058CA2070424AU1991071794