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1. (WO1991007957) METHOD OF TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/007957 International Application No.: PCT/US1989/005405
Publication Date: 13.06.1991 International Filing Date: 29.11.1989
Chapter 2 Demand Filed: 26.06.1991
IPC:
A61K 31/285 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
28
Compounds containing heavy metals
285
Arsenic compounds
Applicants:
UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US/US]; 826 Cathedral of Learning Pittsburgh, PA 15260, US
Inventors:
HO, Monto; US
GUPTA, Phalguni; US
Agent:
SILVERMAN, Arnold, B.; Eckert Seamans Cherin & Mellott 600 Grant Street, 42nd Floor Pittsburgh, PA 15219, US
Priority Data:
Title (EN) METHOD OF TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS
(FR) METHODE DE TRAITEMENT DU VIRUS D'IMMUNODEFICIENCE HUMAINE
Abstract:
(EN) A method of treating a patient for human immunodeficiency virus (HIV) includes administering to the individual patient intravenously a therapeutically effective dosage of oxophenarsine (3 amino-4 hydroxyphenyl-arsineoxide hydrochloride). The dose employed may be up to about 1 milligram per kilogram of body weight administered 1 to 2 times weekly. The oxophenarsine is preferably administered in such an amount as to achieve in said patient a blood serum concentration of about 0.12 to 6.0 micrograms per milliliter.
(FR) Une méthode de traitement d'un patient contre le virus d'immunodéficience humaine HIV comprend l'administration par voie intraveineuse au patient d'un dosage à efficacité thérapeutique d'oxophénarsine (3 amino-4 hydroxyphényle-oxyde d'hydrogène arsénié-hydrochlorure). La dose utilisée peut atteindre environ 1 milligramme par kilogramme de poids du patient, en administration d'une ou deux fois par semaine. L'oxophénarsine est de préférence administrée selon une quantité permettant d'obtenir chez le patient une concentration en sérum sanguin d'environ 0,12 à 6,9 microgrammes par millilitre.
Designated States: AU, JP, KR
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1989046608