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1. (WO1991007955) USE OF NERVONIC ACID AND LONG CHAIN FATTY ACIDS FOR THE TREATMENT OF DEMYELINATING DISORDERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/007955 International Application No.: PCT/GB1990/001870
Publication Date: 13.06.1991 International Filing Date: 30.11.1990
IPC:
A61K 31/20 (2006.01) ,A61K 31/23 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
23
of acids having a carboxyl group bound to a chain of seven or more carbon atoms
Applicants:
CRODA INTERNATIONAL PLC [GB/GB]; Cowick Hall Snaith Goole North Humberside DN14 9AA, GB (AllExceptUS)
COUPLAND, Keith [GB/GB]; GB (UsOnly)
LANGLEY, Nigel, Alan [GB/GB]; GB (UsOnly)
Inventors:
COUPLAND, Keith; GB
LANGLEY, Nigel, Alan; GB
Agent:
SPENCER, Graham, Easdale; A.A. Thornton & Co. Northumberland House 303-306 High Holborn London WC1V 7LE, GB
Priority Data:
8927109.230.11.1989GB
9016660.430.07.1990GB
Title (EN) USE OF NERVONIC ACID AND LONG CHAIN FATTY ACIDS FOR THE TREATMENT OF DEMYELINATING DISORDERS
(FR) UTILISATION D'ACIDE NERVONIQUE ET D'ACIDES GRAS A LONGUES CHAINES DANS LE TRAITEMENT DES TROUBLES PROVOQUES PAR LA DEMYELINISATION
Abstract:
(EN) Compositions containing nervonic acid (cis-tetracos-15-enoic acid) in a physiologically acceptable form are useful in the treatment of demyelinating diseases, such as multiple sclerosis. Additional long chain fatty acids of chain length C16 to C26, especially erucic acid, or their esters, may be included in such compositions.
(FR) Des préparations contenant de l'acide nervonique (acide cistétracos-15-énoïque) sous une forme physiologiquement acceptable sont utiles dans le traitement des maladies de démyélinisation telles que la sclérose en plaques. Des acides gras à chaînes longues supplémentaires, dont la longueur des chaînes est comprise entre C16 et C26, en particulier l'acide érucique, ou leurs esters, peuvent être inclus dans ces préparations.
Designated States: CA, GB, JP, NO, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NO19912943EP0455783US5194448JPH07500566