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1. (WO1991007507) 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/007507 International Application No.: PCT/US1990/006608
Publication Date: 30.05.1991 International Filing Date: 13.11.1990
Chapter 2 Demand Filed: 22.04.1991
IPC:
C07D 311/82 (2006.01) ,C07H 21/00 (2006.01) ,C09B 11/08 (2006.01) ,C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
311
Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02
ortho- or peri-condensed with carbocyclic rings or ring systems
78
Ring systems having three or more relevant rings
80
Dibenzopyrans; Hydrogenated dibenzopyrans
82
Xanthenes
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
C CHEMISTRY; METALLURGY
09
DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
B
ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES; MORDANTS; LAKES
11
Diaryl- or triarylmethane dyes
04
derived from triarylmethanes
06
Hydroxy derivatives of triarylmethanes in which at least one -OH group is bound to an aryl nucleus
08
Phthaleins
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
APPLIED BIOSYSTEMS, INC. [US/US]; 850 Lincoln Centre Drive Foster City, CA 94404, US
Inventors:
MENCHEN, Steven, M.; US
LEE, Linda, G.; US
CONNELL, Charles, R.; US
HERSHEY, N., Davis; US
CHAKERIAN, Vergine; US
WOO, Sam, Lee; US
FUNG, Steven; US
Agent:
SMITH, Joseph, H.; Applied Biosystems, Inc. 850 Lincoln Centre Drive Foster City, CA 94404, US
Priority Data:
436,45514.11.1989US
Title (EN) 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES
(FR) COLORANTS DE 4,7-DICHLOROFLUOROSCEINE UTILISE COMME SONDE MOLECULAIRE
Abstract:
(EN) Long wavelength, narrow emission bandwidth fluorescein dyes are provided for detecting spacially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 1',2',7',8'-dibenzo-4,7-dichlorofluoresceins. Methods of using the dyes in automated DNA sequencing are described.
(FR) Sont décrits des colorants de fluorescéine de longueur d'onde courte à largeur de bande d'émission étroite, permettant de détecter des substances cibles se chevauchant dans l'espace. Les colorants comprennent des 4,7-dichlorofluorescéines, et notamment des 1',2',7',8'-dibenzo-4,7-dichlorofluorescéines. Des procédés d'utilisation des colorants en séquençage d'ADN automatique sont décrits.
Designated States: JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0500779