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1. (WO1991007484) PROTEIN HAVING ACTIVITY LIKE THAT OF HUMAN PROTEIN C AND/OR ACTIVATED HUMAN PROTEIN C
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/007484 International Application No.: PCT/JP1990/001471
Publication Date: 30.05.1991 International Filing Date: 13.11.1990
Chapter 2 Demand Filed: 28.05.1991
IPC:
C12N 9/64 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
48
acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
50
Proteinases
64
derived from animal tissue, e.g. rennin
Applicants:
TEIJIN LIMITED [JP/JP]; 6-7, Minamihommachi 1-chome Chuo-ku Osaka-shi Osaka 541, JP (AllExceptUS)
SUZUKI, Masahiko [JP/JP]; JP (UsOnly)
WAKABAYASHI, Kenji [JP/JP]; JP (UsOnly)
SUMI, Yoshihiko [JP/JP]; JP (UsOnly)
ICHIKAWA, Yataro [JP/JP]; JP (UsOnly)
Inventors:
SUZUKI, Masahiko; JP
WAKABAYASHI, Kenji; JP
SUMI, Yoshihiko; JP
ICHIKAWA, Yataro; JP
Agent:
MAYEDA, Sumihiro; Intellectual Property Department Teijin Limited 1-1, Uchisaiwaicho 2-chome Chiyoda-ku Tokyo 100, JP
Priority Data:
1/29388514.11.1989JP
Title (EN) PROTEIN HAVING ACTIVITY LIKE THAT OF HUMAN PROTEIN C AND/OR ACTIVATED HUMAN PROTEIN C
(FR) PROTEINE POSSEDANT UNE ACTIVITE ANALOGUE A CELLE DE LA PROTEINE C HUMAINE ET/OU DE LA PROTEINE C HUMAINE ACTIVEE
Abstract:
(EN) A human protein C or an activated human protein C having the carboxyl terminal of the light chain thereof deleted so as to form an amino acid sequence as indicated in Table 1 or having the twelve amino acids of the heavy chain as counted from the amino terminal modified into a combination selected from among amino acids as indicated in Table 2; a DNA sequence coding for the same; an expression vector; and a transfected cell.
(FR) On décrit une protéine C humaine ou une protéine C humaine activée dont on a effacé la terminaison carboxyle de la chaîne légère de manière à former une séquence d'acides aminés telle qu'elle apparaît dans le tableau 1, ou dont on a modifié les douze acides aminés dans la chaîne lourde (en comptant à partir de la terminaison amino) de manière à obtenir une combinaison sélectionnée parmi les acides aminés indiqués dans le tableau 2; on décrit également une séquence d'ADN codant ladite protéine, un vecteur d'expression, et une cellule transfectée.
Designated States: US
European Patent Office (DE, FR, GB)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)