Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1991007426) BIOAVAILABLE IRON-ALBUMIN COMPOUNDS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/007426 International Application No.: PCT/EP1990/001878
Publication Date: 30.05.1991 International Filing Date: 09.11.1990
Chapter 2 Demand Filed: 21.05.1991
IPC:
A61K 33/26 (2006.01) ,C07K 1/107 (2006.01) ,C07K 1/113 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
26
Iron; Compounds thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
107
by chemical modification of precursor peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
107
by chemical modification of precursor peptides
113
without change of the primary structure
Applicants:
ITALFARMACO S.P.A. [IT/IT]; Viale Fulvio Testi, 330 I-20126 Milano, IT (AllExceptUS)
CREMONESI, Pietro [IT/IT]; IT (UsOnly)
BARANI, Roberto [IT/IT]; IT (UsOnly)
CARAMAZZA, Ida [IT/IT]; IT (UsOnly)
DEL SOLDATO, Piero [IT/IT]; IT (UsOnly)
Inventors:
CREMONESI, Pietro; IT
BARANI, Roberto; IT
CARAMAZZA, Ida; IT
DEL SOLDATO, Piero; IT
Agent:
BIANCHETTI, Giuseppe; Studio Consulenza Brevettuale Via Rossini, 8 I-20122 Milano, IT
Priority Data:
22399 A/8916.11.1989IT
Title (EN) BIOAVAILABLE IRON-ALBUMIN COMPOUNDS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
(FR) COMPOSES DE FER-ALBUMINES BIODISPONIBLES, LEUR PROCEDE DE PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
Abstract:
(EN) Iron-albumin derivatives are described consisting of albumins acylated with dicarboxylic acid residues and containing high amounts of iron, insoluble at the stomach acid pH and highly soluble at the intestinal pH. The derivatives are characterized by a very low gastrolesivity and toxicity and by remarkable bioavailability and therapeutic effectiveness in the treatment of anaemic conditions.
(FR) Sont décrits des dérivés de fer-albumines, comprenant des albumines acylées à l'aide de résidus d'acide dicarboxylique, et contenant des quantités élevées de fer, insolubles au pH de l'acide gastrique, et hautement solubles au pH intestinal. Les dérivés sont caractérisés par une très faible gastrolésivité et toxicité, et par une biodisponibilité et une efficacité thérapeutique remarquables dans le traitement d'états anémiques.
Designated States: AU, BB, BG, BR, CA, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, RO, SD, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0593443CA2068655AU1991070396