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1. (WO1991007406) DERIVATIVES OF A TRANSITION METAL HAVING A PORPHYRINIC STRUCTURE, AND USE OF THIS DERIVATIVE IN DRUG MANUFACTURING
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/007406 International Application No.: PCT/FR1990/000821
Publication Date: 30.05.1991 International Filing Date: 16.11.1990
Chapter 2 Demand Filed: 06.06.1991
IPC:
C07D 487/22 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
22
in which the condensed system contains four or more hetero rings
Applicants:
I.R.2.M. [FR/FR]; Centre Atria Esplanade Charles-de-Gaulle F-30000 Nîmes, FR (AllExceptUS)
MASSE, Jean-Pierre [FR/FR]; FR (UsOnly)
Inventors:
MASSE, Jean-Pierre; FR
Agent:
PORTAL, Gérard ; Cabinet Beau de Loménie 55, rue d'Amsterdam F-75008 Paris, FR
Priority Data:
89/1527621.11.1989FR
Title (EN) DERIVATIVES OF A TRANSITION METAL HAVING A PORPHYRINIC STRUCTURE, AND USE OF THIS DERIVATIVE IN DRUG MANUFACTURING
(FR) DERIVES DE METAL DE TRANSITION A STRUCTURE PORPHYRINIQUE, UTILISATION DE CE DERIVE POUR LA FABRICATION DE MEDICAMENTS
Abstract:
(EN) Novel organic derivatives of a transition metal having a porphyrinic structure. This novel derivative is characterized in that it consists of a transition metal derivative with an organic compound having a porphyrinic structure, said derivative being of general formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R8 are selected independently among the common substituents of chlorophylls, particularly hydrogen, a straight-, branched- or ring-chain C1-C5 lower alkyl. This derivative is hypoglycaemically active and therefore suited to therapeutical applications.
(FR) L'invention concerne de nouveaux dérivés organiques de métal à transition à structure porphyrinique. Ce nouveau dérivé est caractérisé en ce qu'il est constitué par un dérivé d'un métal de transition avec un composé organique à structure porphyrinique, ledit dérivé répondant à la formule générale (I) dans laquelle R1, R2, R3, R4, R5, R6, R7, R8 sont choisis indépendamment parmi les substituants usuels des chlorophylles, en particulier l'hydrogène, un alkyle inférieur en C1-C5 à chaîne droite, ramifiée ou cyclique. Ce dérivé présente une activité hypoglycémiante ce qui le rend avantageux pour une application thérapeutique.
Designated States: AU, BR, CA, HU, JP, KR, MC, MG, NO, RO, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
AU1990067475