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1. (WO1991007178) PYRIMIDONE DERIVATIVES AND ANALOGS IN THE TREATMENT OF ASTHMA OR CERTAIN SKIN DISORDERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/007178 International Application No.: PCT/US1990/002162
Publication Date: 30.05.1991 International Filing Date: 20.04.1990
Chapter 2 Demand Filed: 20.02.1991
IPC:
A61K 31/415 (2006.01) ,A61K 31/505 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
415
1,2-Diazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Applicants:
PFIZER INC. [US/US]; 235 East 42nd Street New York, NY 10017, US (AllExceptUS)
CHENG, John, B. [US/US]; US (UsOnly)
Inventors:
CHENG, John, B.; US
Agent:
RICHARDSON, Peter, C. ; Pfizer Inc. 235 East 42nd Street New York, NY 10017, US
Priority Data:
PCT/US89/0522113.11.1989US
Title (EN) PYRIMIDONE DERIVATIVES AND ANALOGS IN THE TREATMENT OF ASTHMA OR CERTAIN SKIN DISORDERS
(FR) DERIVES DE LA PYRIMIDONE ET ANALOGUES POUR LE TRAITEMENT DE L'ASTHME OU CERTAINES AFFECTIONS DE LA PEAU
Abstract:
(EN) Racemic or optically active compound of formula (I), wherein X is O or NH, R1 is a (C7-C11)polycycloalkyl group, R2 is methyl or ethyl, Y is (II) or (III), R3 is hydrogen, (C1-C3)alkyl, (C2-C3)alkenyl, benzyl or phenethyl, and R4 is hydrogen, (C1-C3)alkyl or (C2-C3)alkanoyl, are useful in the treatment of asthma or inflammatory airway or skin diseases.
(FR) Composé racémique ou optiquement actif de formule (I), où X est O ou NH, R1 est un groupe polycycloalkyle (C7-C11), R2 est méthyle ou éthyle, Y est (II) ou (III); R3 est hydrogène, (C1-C3)alkyle, (C2-C3)alkényle, benzyle ou phénétyle et R4 est hydrogène, (C1-C3)alkyle ou (C2-C3)alkanoyle, utile dans le traitement de l'asthme ou des maladies de la peau ou des voies respiratoires.
Designated States: FI, HU, NO, RO, SU, US
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US5342842