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1. (WO1991006867) ECHINODERM AGGLUTININ AND METHOD OF EXTRACTION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/006867 International Application No.: PCT/CA1990/000371
Publication Date: 16.05.1991 International Filing Date: 29.10.1990
Chapter 2 Demand Filed: 31.05.1991
IPC:
C07K 14/435 (2006.01) ,G01N 33/569 (2006.01) ,G01N 33/579 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
579
involving limulus lysate
Applicants:
ATLANTIC INSTITUTE OF BIOTECHNOLOGY [CA/CA]; 1046 Barrington Street Suite 112 Halifax, Nova Scotia B3H 2R1, CA (AllExceptUS)
WARDLAW, Alastair, Connell [GB/GB]; GB (UsOnly)
MOSELEY, Charles, Maxwell [CA/CA]; CA (UsOnly)
Inventors:
WARDLAW, Alastair, Connell; GB
MOSELEY, Charles, Maxwell; CA
Agent:
SMART & BIGGAR; 900-55 Metcalfe Street P.O. Box 2999, Station "D" Ottawa, Ontario K2P 5Y6, CA
Priority Data:
2,002,00001.11.1989CA
Title (EN) ECHINODERM AGGLUTININ AND METHOD OF EXTRACTION
(FR) AGGLUTININE D'ECHINODERME ET PROCEDE D'EXTRACTION ASSOCIE
Abstract:
(EN) A method is disclosed for extracting an endotoxin-detecting agglutinin from the coelomic fluid of Echinoderms of the Subclass Regularia. The product is useful in detecting Gram-negative bacteria, endotoxins and endotoxin contamination of injectable and intravenous fluid and medical devices. The product is an alternative to the expensive Limulus Amoebocyte Lysate reagent.
(FR) Le procédé décrit sert à extraire une agglutinine, ayant la propriété de détecter l'endotoxine, du fluide c÷lomique des equinodermes de la sous-classe $i(Regularia). Ce produit sert à détecter la présence de bactéries Gram-négatives, d'endotoxines et de sources de contamination par endotoxines dans des fluides d'injection et dans des fluides intraveineux ainsi que dans des dispositifs médicaux. Ce produit permet de remplacer avantageusement le réactif à base de lysat d'amibocytes de limule, qui est un produit de même utilité mais plus coûteux.
Designated States: AU, DK, JP, NO, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0498820JPH06504112AU1990066137