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1. (WO1991006866) URINARY TUMOR ASSOCIATED ANTIGEN, ANTIGENIC SUBUNITS USES AND METHODS OF DETECTION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/006866 International Application No.: PCT/US1990/006339
Publication Date: 16.05.1991 International Filing Date: 31.10.1990
Chapter 2 Demand Filed: 01.06.1991
IPC:
A61K 38/00 (2006.01) ,A61K 39/00 (2006.01) ,A61K 47/48 (2006.01) ,A61K 49/00 (2006.01) ,C07K 14/47 (2006.01) ,C07K 16/30 (2006.01) ,C07K 16/42 (2006.01) ,G01N 33/574 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
30
from tumour cells
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
42
against immunoglobulins (anti-idiotypic antibodies)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
Applicants:
MORTON, Donald, L. [US/US]; US
GUPTA, Rishab, K. [IN/US]; US
EUHUS, David, M. [US/US]; US
Inventors:
MORTON, Donald, L.; US
GUPTA, Rishab, K.; US
EUHUS, David, M.; US
Agent:
CAMPBELL, Cathryn ; Pretty, Schroeder, Brueggemann & Clark 444 South Flower Street Suite 2000 Los Angeles, CA 90071, US
UEXKÜLL & STOLBERG; Beselerstr. 4 D-2000 Hamburg 52, DE
Priority Data:
431,53303.11.1989US
Title (EN) URINARY TUMOR ASSOCIATED ANTIGEN, ANTIGENIC SUBUNITS USES AND METHODS OF DETECTION
(FR) ANTIGENE ASSOCIE A DES TUMEURS URINAIRES, EMPLOIS DE SOUS-UNITES ANTIGENIQUES ET PROCEDES DE DETECTION
Abstract:
(EN) The invention provides a substantially purified antigenic polypeptide of urinary tumor associated antigen having, after reuction by beta-mercaptoethanol and separation by SDS-polyacrylamide gel electrophoresis, a molecular weight of about 90 to 100 kD. Monoclonal antibodies, methods of detecting cancers, methods of immunotherapy, methods for monitoring a malignancy, a method of detecting urinary tumor associated antigen, tumor cell vaccines or polypeptide vaccine and other methods relating to urinary tumor associated antigen are also provided.
(FR) Polypeptide antigénique purifié d'antigène associé à des tumeurs urinaires ayant, après réduction par $g(b)-mercaptoéthanol et séparation par électrophorèse par gel SDS-polyacrylamide, une masse moléculaire comprise entre environ 90 et 100 kD. On décrit également des anticorps monoclonaux, des procédés de détection de cancers, des procédés d'immunothérapie, des procédés de contrôle d'une malignité, un procédé de détection d'antigène associé à des tumeurs urinaires, des vaccins contre les cellules tumorales ou un vaccin polypeptidique ainsi que d'autres procédés relatifs à l'antigène associé à des tumeurs urinaires.
Designated States: AT, AU, BB, BG, BR, CA, CH, DE, DK, ES, FI, GB, HU, JP, KP, KR, LK, LU, MC, MG, MW, NL, NO, RO, SD, SE, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0498851EP0678744ES2084715JP3423306JPH05505596JP2001281255
CA2331088CA2072620DE000069024659DE000069033295AU1991068753DK0498851