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1. (WO1991006860) HYBRIDOMAS AND MONOCLONAL ANTIBODIES THEREFROM REACTIVE TOWARD ANTIGENS FROM $i(EDWARDSIELLA ICTALURI)
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/006860 International Application No.: PCT/US1990/006232
Publication Date: 16.05.1991 International Filing Date: 01.11.1990
Chapter 2 Demand Filed: 01.11.1990
IPC:
C07K 16/12 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
12
against material from bacteria
Applicants:
THE UNITED STATES OF AMERICA, represented by THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE [US/US]; Washington, DC 20231, US
Inventors:
KLESIUS, Phillip, H.; US
Agent:
OLIFF, James, A. ; Oliff & Berridge P.O. Box 19928 Alexandria, VA 22320, US
Priority Data:
431,34803.11.1989US
Title (EN) HYBRIDOMAS AND MONOCLONAL ANTIBODIES THEREFROM REACTIVE TOWARD ANTIGENS FROM $i(EDWARDSIELLA ICTALURI)
(FR) HYBRIDOMES ET LEURS ANTICORPS MONOCLONAUX, REAGISSANT AVEC LES ANTIGENES DE L'$i(EDWARDSIELLA ICTALURI)
Abstract:
(EN) A hybridoma cell line produces a monoclonal antibody with reactivity directed specifically to immunodominant antigens from the catfish pathogen $i(Edwardsiella ictaluri), the antigens having molecular weights of about 14,000, 39,000, 48,000, 60,000, 66,000, 83,000, and 93,000 daltons. This antibody is specific for proteins of $i(E. ictaluri) but not for other catfish pathogens. It is therefore useful for the positive identification of $i(E. ictaluri) from body fluids and tissue of catfish and for identification and purification of the reactive immunodominant antigens.
(FR) Une lignée cellulaire d'hybridome produit un anticorps monoclonal dont la réactivité est spécifique aux antigènes immuno-dominants de l'agent pathogène $i(Edwardsiella ictaluri) du poisson-chat. Ces antigènes ont des masses moléculaires d'environ 14.000, 39.000, 48.000, 60.000, 66.000, 83.000 et 93.000 daltons. Cet anticorps est spécifique aux protéines de $i(E. ictaluri) mais pas aux autres agents pathogènes du poisson-chat. Il est donct utile à l'identification positive de $i(E. ictaluri) dans les fluides de l'organisme et le tissu du poisson-chat, ainsi qu'à l'identification et à la purification des antigènes immuno-dominants réactifs.
Designated States: CA
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA2072741